Microneedle-mediated vaccination: innovation and translation
Vaccine administration by subcutaneous or intramuscular injection is the most commonly
prescribed route for inoculation, however, it is often associated with some deficiencies such …
prescribed route for inoculation, however, it is often associated with some deficiencies such …
Polymeric microneedles for transdermal protein delivery
The intrinsic properties of therapeutic proteins generally present a major impediment for
transdermal delivery, including their relatively large molecule size and susceptibility to …
transdermal delivery, including their relatively large molecule size and susceptibility to …
Microneedles as the technique of drug delivery enhancement in diverse organs and tissues
AS Rzhevskiy, TRR Singh, RF Donnelly… - Journal of controlled …, 2018 - Elsevier
Microneedles is the technique of drug delivery enhancement, which was primarily designed
for facilitating percutaneous drug delivery. Started from the development of simple solid …
for facilitating percutaneous drug delivery. Started from the development of simple solid …
Skin permeabilization for transdermal drug delivery: recent advances and future prospects
CM Schoellhammer, D Blankschtein… - Expert opinion on drug …, 2014 - Taylor & Francis
Introduction: Transdermal delivery has potential advantages over other routes of
administration. It could reduce first-pass metabolism associated with oral delivery and is less …
administration. It could reduce first-pass metabolism associated with oral delivery and is less …
Enterotoxigenic Escherichia coli in Developing Countries: Epidemiology, Microbiology, Clinical Features, Treatment, and Prevention
SUMMARY ETEC is an underrecognized but extremely important cause of diarrhea in the
developing world where there is inadequate clean water and poor sanitation. It is the most …
developing world where there is inadequate clean water and poor sanitation. It is the most …
Transdermal delivery systems for biomolecules
MC Peña-Juárez, OR Guadarrama-Escobar… - Journal of …, 2021 - Springer
Purpose The present review article focuses on highlighting the main technologies used as
tools that improve the delivery of transdermal biomolecules, addressing them from the point …
tools that improve the delivery of transdermal biomolecules, addressing them from the point …
Needle-free vaccine delivery
EL Giudice, JD Campbell - Advanced drug delivery reviews, 2006 - Elsevier
The search for methods of vaccine delivery not requiring a needle and syringe has been
accelerated by recent concerns regarding pandemic disease, bioterrorism, and disease …
accelerated by recent concerns regarding pandemic disease, bioterrorism, and disease …
Recent advances in the discovery and delivery of vaccine adjuvants
DT O'Hagan, NM Valiante - Nature Reviews Drug Discovery, 2003 - nature.com
Adjuvant design has historically had a touch of alchemy at its heart due to its reliance on the
complex biology of innate immune activation. However, a new mechanistic understanding of …
complex biology of innate immune activation. However, a new mechanistic understanding of …
Elastic liposomes as novel carriers: recent advances in drug delivery
A Hussain, S Singh, D Sharma, TJ Webster… - International journal …, 2017 - Taylor & Francis
Elastic liposomes (EL) are some of the most versatile deformable vesicular carriers that
comprise physiologically biocompatible lipids and surfactants for the delivery of numerous …
comprise physiologically biocompatible lipids and surfactants for the delivery of numerous …
Immunization without needles
S Mitragotri - Nature Reviews Immunology, 2005 - nature.com
Most current immunization procedures make use of needles and syringes for vaccine
administration. With the increase in the number of immunizations that children around the …
administration. With the increase in the number of immunizations that children around the …