Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease

P Kesika, N Suganthy, BS Sivamaruthi, C Chaiyasut - Life sciences, 2021 - Elsevier
Gut microbiota represents a diverse and dynamic population of microorganisms harboring
the gastrointestinal tract, which influences the host health and disease. Gut microbiota …

[HTML][HTML] Brain-gut-microbiota axis in Alzheimer's disease

K Kowalski, A Mulak - Journal of neurogastroenterology and …, 2019 - ncbi.nlm.nih.gov
Disturbances along the brain-gut-microbiota axis may significantly contribute to the
pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …

Genetic correlations between Alzheimer's disease and gut microbiome genera

D Cammann, Y Lu, MJ Cummings, ML Zhang… - Scientific Reports, 2023 - nature.com
A growing body of evidence suggests that dysbiosis of the human gut microbiota is
associated with neurodegenerative diseases like Alzheimer's disease (AD) via …

Microbiota-brain-gut axis and neurodegenerative diseases

EMM Quigley - Current neurology and neuroscience reports, 2017 - Springer
Abstract Purpose of Review The purposes of this review were as follows: first, to provide an
overview of the gut microbiota and its interactions with the gut and the central nervous …

Periodontal microorganisms and Alzheimer disease–A causative relationship?

G Jungbauer, A Stähli, X Zhu… - Periodontology …, 2022 - Wiley Online Library
In the initiation or exacerbation of Alzheimer disease, the dissemination of oral
microorganisms into the brain tissue or the low‐level systemic inflammation have been …

The gut microbiome in human neurological disease: a review

H Tremlett, KC Bauer, S Appel‐Cresswell… - Annals of …, 2017 - Wiley Online Library
Almost half the cells and 1% of the unique genes found in our bodies are human, the rest
are from microbes, predominantly bacteria, archaea, fungi, and viruses. These …

The human gut microbiome in health and disease

J Jovel, LA Dieleman, D Kao, AL Mason, E Wine - Metagenomics, 2018 - Elsevier
The harmonic coexistence of microorganisms with the human body is the result of a long
coevolutionary process that has minimized competition for nutrients and immunological …

Gram-negative bacterial molecules associate with Alzheimer disease pathology

X Zhan, B Stamova, LW Jin, C DeCarli, B Phinney… - Neurology, 2016 - AAN Enterprises
Objective: We determined whether Gram-negative bacterial molecules are associated with
Alzheimer disease (AD) neuropathology given that previous studies demonstrate Gram …

Periodontitis and cognitive decline in Alzheimer's disease

M Ide, M Harris, A Stevens, R Sussams, V Hopkins… - PloS one, 2016 - journals.plos.org
Periodontitis is common in the elderly and may become more common in Alzheimer's
disease because of a reduced ability to take care of oral hygiene as the disease progresses …

Lipopolysaccharide associates with amyloid plaques, neurons and oligodendrocytes in Alzheimer's disease brain: a review

X Zhan, B Stamova, FR Sharp - Frontiers in aging neuroscience, 2018 - frontiersin.org
This review proposes that lipopolysaccharide (LPS, found in the wall of all Gram-negative
bacteria) could play a role in causing sporadic Alzheimer's disease (AD). This is based in …