Solid‐phase extraction methods for nucleic acid separation. A review

P Li, M Li, D Yue, H Chen - Journal of Separation Science, 2022 - Wiley Online Library
The separation and purification of biomacromolecules such as nucleic acid is a perpetual
topic in separation processes and bioengineering (fine chemicals, biopharmaceutical …

A review on recent developments for biomolecule separation at analytical scale using microfluidic devices

KKR Tetala, MA Vijayalakshmi - Analytica chimica acta, 2016 - Elsevier
Microfluidic devices with their inherent advantages like the ability to handle 10− 9 to 10− 18
L volume, multiplexing of microchannels, rapid analysis and on-chip detection are proving to …

Rapid SARS-CoV-2 nucleic acid testing and pooled assay by tetrahedral DNA nanostructure transistor

X Wang, D Kong, M Guo, L Wang, C Gu, C Dai… - Nano …, 2021 - ACS Publications
Direct SARS-CoV-2 nucleic acid testing with fast speed and high frequency is crucial for
controlling the COVID-19 pandemic. Here, direct testing of SARS-CoV-2 nucleic acid is …

Aptamer-based-sorbents for sample treatment—a review

V Pichon, F Brothier, A Combès - Analytical and Bioanalytical Chemistry, 2015 - Springer
To improve selectivity during sample pretreatment, various selective tools inducing a
molecular recognition mechanism during the extraction procedure have been developed …

High‐κ solid‐gate transistor configured graphene biosensor with fully integrated structure and enhanced sensitivity

C Wang, Y Li, Y Zhu, X Zhou, Q Lin… - Advanced Functional …, 2016 - Wiley Online Library
A fully integrated graphene field‐effect transistor (GFET) nanosensor utilizing a novel high‐κ
solid‐gating geometry for a practical biosensor with enhanced sensitivity is presented …

Aptamers against immunoglobulins: Design, selection and bioanalytical applications

Z Bognár, RE Gyurcsányi - International Journal of Molecular Sciences, 2020 - mdpi.com
Nucleic acid aptamers show clear promise as diagnostic reagents, as highly specific strands
were reported against a large variety of biomarkers. They have appealing benefits in terms …

An aptameric graphene nanosensor for label-free detection of small-molecule biomarkers

C Wang, J Kim, Y Zhu, J Yang, GH Lee, S Lee… - Biosensors and …, 2015 - Elsevier
This paper presents an aptameric graphene nanosensor for detection of small-molecule
biomarkers. To address difficulties in direct detection of small molecules associated with …

Magnetofection and isolation of DNA using polyethyleneimine functionalized magnetic iron oxide nanoparticles

AN Danthanarayana… - Royal Society …, 2018 - royalsocietypublishing.org
This study was carried out to develop a simple and efficient method to isolate DNA directly
from biological samples using iron oxide nanoparticles (IONPs) functionalized with …

Molecular separation by using active and passive microfluidic chip designs: a comprehensive review

A Ebrahimi, K Icoz, R Didarian, CH Shih… - Advanced Materials …, 2024 - Wiley Online Library
Separation and identification of molecules and biomolecules such as nucleic acids, proteins,
and polysaccharides from complex fluids are known to be important due to unmet needs in …

Integrated microfluidic isolation of aptamers using electrophoretic oligonucleotide manipulation

J Kim, TR Olsen, J Zhu, JP Hilton, KA Yang, R Pei… - Scientific reports, 2016 - nature.com
We present a microfluidic approach to integrated isolation of DNA aptamers via systematic
evolution of ligands by exponential enrichment (SELEX). The approach employs a …