Regulation of GATA1 levels in erythropoiesis

L Gutiérrez, N Caballero, L Fernández‐Calleja… - IUBMB …, 2020 - Wiley Online Library
GATA1 is considered as the “master” transcription factor in erythropoiesis. It regulates at the
transcriptional level all aspects of erythroid maturation and function, as revealed by gene …

In-vitro evaluation of apoptotic effect of OEO and thymol in 2D and 3D cell cultures and the study of their interaction mode with DNA

T Jamali, G Kavoosi, M Safavi, SK Ardestani - Scientific Reports, 2018 - nature.com
Oliveria decumbens is an Iranian endemic plant used extensively in traditional medicine.
Recently, some studies have been performed on biological effects of Oliveria essential oil …

3D tumor spheroids: Morphological alterations a yardstick to anti-cancer drug response

A Senrung, S Lalwani, D Janjua, T Tripathi, J Kaur… - In vitro models, 2023 - Springer
Tumor spheroids are one of the well-characterized 3D culture systems bearing close
resemblance to the physiological tissue organization and complexity of avascular solid …

Ablation of Gata1 in adult mice results in aplastic crisis, revealing its essential role in steady-state and stress erythropoiesis

L Gutiérrez, S Tsukamoto, M Suzuki… - Blood, The Journal …, 2008 - ashpublications.org
The transcription factor Gata1 is expressed in several hematopoietic lineages and plays
essential roles in normal hematopoietic development during embryonic stages. The lethality …

Application of hanging drop technique for stem cell differentiation and cytotoxicity studies

M Banerjee, RR Bhonde - Cytotechnology, 2006 - Springer
The aim of our study is to explore the possibility of using an ancient method of culture
technique-the hanging drop technique for stem cell differentiation and cytotoxicity testing …

Formation and hematopoietic differentiation of human embryoid bodies by suspension and hanging drop cultures

C Cerdan, SH Hong, M Bhatia - Current protocols in stem cell …, 2007 - Wiley Online Library
The in vitro aggregation of human embryonic stem cells (hESCs) into clusters termed
embryoid bodies (EBs) allows for the spontaneous differentiation of cells representing …

[HTML][HTML] Multiparameter comparisons of embryoid body differentiation toward human stem cell applications

SH Hong, T Werbowetski-Ogilvie, V Ramos-Mejia… - Stem cell …, 2010 - Elsevier
Applications of differentiated progeny generated from human embryonic stem cells (hESCs)
broadly span cell replacement therapies and screening studies (toxicology, disease-drug …

Seamless combination of fluorescence-activated cell sorting and hanging-drop networks for individual handling and culturing of stem cells and microtissue spheroids

A Birchler, M Berger, V Jäggin, T Lopes… - Analytical …, 2016 - ACS Publications
Open microfluidic cell culturing devices offer new possibilities to simplify loading, culturing,
and harvesting of individual cells or microtissues due to the fact that liquids and …

Dynamic regulation of Gata factor levels is more important than their identity

R Ferreira, A Wai, R Shimizu… - Blood, The Journal …, 2007 - ashpublications.org
Abstract Three Gata transcription factors (Gata1,-2, and-3) are essential for hematopoiesis.
These factors are thought to play distinct roles because they do not functionally replace each …

GATA-1 genome-wide occupancy associates with distinct epigenetic profiles in mouse fetal liver erythropoiesis

GL Papadopoulos, E Karkoulia… - Nucleic acids …, 2013 - academic.oup.com
We report the genomic occupancy profiles of the key hematopoietic transcription factor
GATA-1 in pro-erythroblasts and mature erythroid cells fractionated from day E12. 5 mouse …