Genetics of age-related macular degeneration (AMD)
MM DeAngelis, LA Owen, MA Morrison… - Human molecular …, 2017 - academic.oup.com
Age-related macular degeneration (AMD) is a progressive blinding disease and represents
the leading cause of visual impairment in the aging population. AMD affects central vision …
the leading cause of visual impairment in the aging population. AMD affects central vision …
Biomarkers as predictive factors of anti-VEGF response
M Bobadilla, A Pariente, AI Oca, R Peláez… - Biomedicines, 2022 - mdpi.com
Age-related macular degeneration is the main cause of irreversible vision in developed
countries, and intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections are …
countries, and intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections are …
Genetic variants of complement factor H Y402H (rs1061170), C2 R102G (rs2230199), and C3 E318D (rs9332739) and response to intravitreal anti-VEGF treatment in …
A Kubicka-Trząska, K Żuber-Łaskawiec, S Dziedzina… - Medicina, 2022 - mdpi.com
Background and Objectives: To assess the association between the single nucleotide
polymorphisms (SNPs) in the genes encoding complement factors CFH, C2, and C3 (Y402H …
polymorphisms (SNPs) in the genes encoding complement factors CFH, C2, and C3 (Y402H …
Systemic levels of interleukin‐6 in patients with age‐related macular degeneration: a systematic review and meta‐analysis
A Nahavandipour, M Krogh Nielsen… - Acta …, 2020 - Wiley Online Library
Age‐related macular degeneration (AMD) is the most prevalent cause of irreversible vision
loss in industrialized countries. Several studies have investigated systemic interleukin‐6 (IL …
loss in industrialized countries. Several studies have investigated systemic interleukin‐6 (IL …
Exploring the use of molecular biomarkers for precision medicine in age-related macular degeneration
L Lorés-Motta, EK de Jong, AI den Hollander - Molecular diagnosis & …, 2018 - Springer
Precision medicine aims to improve patient care by adjusting medication to each patient's
individual needs. Age-related macular degeneration (AMD) is a heterogeneous eye disease …
individual needs. Age-related macular degeneration (AMD) is a heterogeneous eye disease …
VEGFA Haplotype and VEGF-A and VEGF-R2 Protein Associations with Exudative Age-Related Macular Degeneration
A Vilkeviciute, D Cebatoriene, L Kriauciuniene… - Cells, 2022 - mdpi.com
Our study aimed to reveal the associations between VEGFA SNPs (rs1570360, rs699947,
rs3025033, and rs2146323), their haplotypes, VEGF-A and VEGF-R2 serum concentrations …
rs3025033, and rs2146323), their haplotypes, VEGF-A and VEGF-R2 serum concentrations …
Association of the CFH Y402H polymorphism with the 1-year response of exudative AMD to intravitreal anti-VEGF treatment in the Brazilian population
FMC Medina, AAL Motta, WY Takahashi… - Ophthalmic …, 2019 - karger.com
Aim: Evidence of the relationship between the polymorphism of the complement factor H
(CFH) gene at position 402 (Y402H) and the response to the treatment of wet AMD is …
(CFH) gene at position 402 (Y402H) and the response to the treatment of wet AMD is …
Inherited eye diseases in Turkey: Current approaches and future directions
F Yaylacioglu Tuncay, S Guntekin Ergun… - American Journal of …, 2020 - Wiley Online Library
The aim of this review is to reveal Turkey's current status of medical practice in inherited eye
diseases and the necessary steps to improve healthcare services and research activities in …
diseases and the necessary steps to improve healthcare services and research activities in …
Association of the Complement Factor H Y402H Polymorphism and Response to Anti-Vascular Endothelial Growth Factor Treatment in Age-Related Macular …
Introduction: Anti-vascular endothelial growth factor (anti-VEGF) agents have a variable
effect on patients with age-related macular degeneration (AMD) that has been attributed to …
effect on patients with age-related macular degeneration (AMD) that has been attributed to …
Aortic stiffness and systemic inflammation changes predict clinical response to intravitreal anti-vascular endothelial growth factor therapy in patients with age-related …
N Ioakeimidis, I Gourgouli… - Journal of Human …, 2023 - nature.com
Aortic stiffness and systemic inflammation are predictors of cardiovascular risk. Anti-vascular
endothelial growth factor agents (anti-VEGF), injected intravitreally, can reverse the course …
endothelial growth factor agents (anti-VEGF), injected intravitreally, can reverse the course …