A perspective on the standards describing mass spectrometry-based metabolic phenotyping (metabolomics/metabonomics) studies in publications

ID Wilson, G Theodoridis, C Virgiliou - Journal of Chromatography B, 2021 - Elsevier
As metabolic phenotyping (metabolomics, metabonomics and also lipidomics) gains in
popularity and new investigators enter the field, the need to maintain and improve standards …

Integrated pharmacokinetics and pharmacometabolomics to reveal the synergistic mechanism of a multicomponent Chinese patent medicine, Mailuo Shutong pills …

X Wang, M Wang, Y Chu, P Zhou, X Zhang, J Zou… - Phytomedicine, 2023 - Elsevier
Abstract Background Mailuo Shutong Pills (MLST) have displayed pharmacological activity
against thromboangiitis obliterans (TAO). However, the active ingredients and therapeutic …

Identifying quality markers of Mailuoshutong pill against thromboangiitis obliterans based on chinmedomics strategy

Y Chu, M Wang, X Wang, X Zhang, L Liu, Y Shi, L Zuo… - Phytomedicine, 2022 - Elsevier
Background Mailuoshutong pill (MLSTP) is a traditional Chinese medicine (TCM) for the
treatment of Thromboangiitis obliterans (TAO, Buerger's disease) which is a segmental non …

Relationship between sphingolipids-mediated neuroinflammation and alcohol use disorder

XJ Cui, JZ Li, CS Wang, HM Ishaq, RL Zhang… - Pharmacology …, 2023 - Elsevier
Background Alcohol use disorder is a chronic recurrent encephalopathy, and its
pathogenesis has not been fully understood. Among possible explanations …

[HTML][HTML] Application of a hybrid zwitterionic hydrophilic interaction liquid chromatography column in metabolic profiling studies

A Lioupi, C Virgiliou, TH Walter, KM Smith… - … of Chromatography A, 2022 - Elsevier
Metabolic phenotyping studies using mouse liver extracts as a model, performed on a novel
zwitterionic HILIC UHPLC column, which is based on ethylene-bridged hybrid …

[HTML][HTML] Metabolome and transcriptome analyses of plants grown in naturally attenuated soil after hydrogen fluoride exposure

J Jo, J Lee, Y Ahn, YS Hwang, J Park, J Lee… - Journal of Hazardous …, 2022 - Elsevier
Accidental chemical leaks and illegal chemical discharges are a global environmental issue.
In 2012, a hydrogen fluoride leak in Gumi, South Korea, killed several people and …

[HTML][HTML] Metabolic Phenotyping Study of Mouse Brain Following Microbiome Disruption by C. difficile Colonization

O Deda, M Kachrimanidou, EG Armitage… - Metabolites, 2022 - mdpi.com
Clostridioides difficile infection (CDI) is responsible for an increasing number of cases of
post-antibiotic diarrhea worldwide, which has high severity and mortality among hospitalized …

Improved discrimination of disease states using proteomics data with the updated Aristotle classifier

D Hua, H Desaire - Journal of proteome research, 2021 - ACS Publications
Mass spectrometry data sets from omics studies are an optimal information source for
discriminating patients with disease and identifying biomarkers. Thousands of proteins or …

[HTML][HTML] Evaluation of Cocaine Effect on Endogenous Metabolites of HepG2 Cells Using Targeted Metabolomics

A Krokos, O Deda, C Virgiliou, H Gika, N Raikos… - Molecules, 2021 - mdpi.com
Cocaine toxicity has been a subject of study because cocaine is one of the most common
and potent drugs of abuse. In the current study the effect of cocaine on human liver cancer …

[HTML][HTML] Plasma Lipidomic and Metabolomic Profiling after Birth in Neonates Born to SARS-CoV-2 Infected and Non-Infected Mothers at Delivery: Preliminary Results

A Kontou, C Virgiliou, T Mouskeftara, O Begou… - Metabolites, 2021 - mdpi.com
Pregnant women are among the high-risk populations for COVID-19, whereas the risk of
vertical transmission to the fetus is very low. Nevertheless, metabolic alternations described …