Precision medicine holds great promise to harness genetic and epigenetic cues for targeted
treatment of a variety of diseases, ranging from many types of cancers, neurodegenerative …

Nm (2′-O-methylation) is one of the most common modifications in the RNA world. It has
the potential to influence the RNA molecules in multiple ways, such as structure, stability …

Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …

Western medicine often aims to specifically treat diseased tissues or organs. However, the
majority of current therapeutics failed to do so owing to their limited selectivity and the …

High-resolution structural studies are essential for understanding the folding and function of
diverse RNAs. Herein, we present a nanoarchitectural engineering strategy for efficient …

An important current issue of modern molecular medicine and biotechnology is the search
for new approaches to early diagnostic assays and adequate therapy of infectious diseases …

Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …

The last two decades have witnessed the development and application of nucleic acid
aptamers in a variety of fields, including target analysis, disease therapy, and molecular and …

The last decade has seen a robust increase in various types of novel RNA molecules and
their complexity in gene regulation. RNA molecules play a critical role in cellular events by …

Aptamers are short oligonucleotides capable of binding specifically to various targets (ie,
small molecules, proteins, and whole cells) which have been introduced in biosensors such …