Physiology and pathophysiology of human airway mucus
The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
[HTML][HTML] SERS sensing for cancer biomarker: Approaches and directions
L Vázquez-Iglesias, GMS Casagrande, D García-Lojo… - Bioactive Materials, 2024 - Elsevier
These days, cancer is thought to be more than just one illness, with several complex
subtypes that require different screening approaches. These subtypes can be distinguished …
subtypes that require different screening approaches. These subtypes can be distinguished …
Airway mucus in pulmonary diseases: Muco-adhesive and muco-penetrating particles to overcome the airway mucus barriers
Airway mucus is a complex viscoelastic gel that provides a defensive physical barrier and
shields the airway epithelium by trapping inhaled foreign pathogens and facilitating their …
shields the airway epithelium by trapping inhaled foreign pathogens and facilitating their …
Untangling mucosal drug delivery: engineering, designing, and testing nanoparticles to overcome the mucus barrier
J Watchorn, AJ Clasky, G Prakash… - ACS Biomaterials …, 2022 - ACS Publications
Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …
the human body. High vascularization and accessibility have motivated drug delivery to …
The changing landscape of the cystic fibrosis lung environment: from the perspective of Pseudomonas aeruginosa
MA Greenwald, MC Wolfgang - Current Opinion in Pharmacology, 2022 - Elsevier
This review guides the reader through the current understanding of the dynamic changes
that occur within the cystic fibrosis (CF) lung that allow Pseudomonas aeruginosa to become …
that occur within the cystic fibrosis (CF) lung that allow Pseudomonas aeruginosa to become …
The lung, the niche, and the microbe: Exploring the lung microbiome in cancer and immunity
M Huynh, MJ Crane, AM Jamieson - Frontiers in Immunology, 2023 - frontiersin.org
The lung is a complex and unique organ system whose biology is strongly influenced by
environmental exposure, oxygen abundance, connection to extrapulmonary systems via a …
environmental exposure, oxygen abundance, connection to extrapulmonary systems via a …
Cystic fibrosis mucus model to design more efficient drug therapies
Mucus represents a strong barrier to tackle for oral or pulmonary administered drugs,
especially in mucus-related disorders. This study uses a pathological cystic fibrosis (CF) …
especially in mucus-related disorders. This study uses a pathological cystic fibrosis (CF) …
Mucins as potential biomarkers for early detection of cancer
Simple Summary Early cancer detection is a challenge in treating cancer patients.
Remarkably, carcinomas of the breast, lung, liver, pancreas, ovary, and colon contribute to …
Remarkably, carcinomas of the breast, lung, liver, pancreas, ovary, and colon contribute to …
Applying next-generation sequencing and multi-omics in chronic obstructive pulmonary disease
PY Tiew, OW Meldrum, SH Chotirmall - International journal of molecular …, 2023 - mdpi.com
Microbiomics have significantly advanced over the last decade, driven by the widespread
availability of next-generation sequencing (NGS) and multi-omic technologies. Integration of …
availability of next-generation sequencing (NGS) and multi-omic technologies. Integration of …
Immunomodulatory properties of vitamin D in the intestinal and respiratory systems
Vitamin D plays a crucial role in modulating the innate immune response by interacting with
its intracellular receptor, VDR. In this review, we address vitamin D/VDR signaling and how it …
its intracellular receptor, VDR. In this review, we address vitamin D/VDR signaling and how it …