Bipolar disorder (BD) is a mood disorder with subtypes characterized by episodes of mania,
hypomania, and/or depression. BD is associated with substantial economic burden, and the …

Objective: We reviewed important clinical aspects of bipolar depression, a progressive
psychiatric condition that is commonly treated in primary care. Bipolar depression is …

Background Bipolar disorder is characterized by debilitating episodes of depression and
mood elevation (mania or hypomania). For most patients, depressive symptoms are more …

Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major
clinical challenge. Main reasons for this include the higher prevalence of depressive relative …

Background The objective of this study was to present 12-month and lifetime prevalence,
correlates, comorbidity, treatment and disability of DSM-5 bipolar I disorder. Methods …

Objective: Cariprazine, a dopamine D3/D2 and 5-HT1A receptor partial agonist, was found
to be effective in treating bipolar I depression in a previous phase 2 study. This phase 3 …

Background Bipolar disorder (BD) is a chronic condition with a high relapse rate, morbidity
and psychosocial impairment that often persist despite pharmacotherapy, highlighting the …

Gigante AD, Bond DJ, Lafer B, Lam RW, Young LT, Yatham LN. Brain glutamate levels
measured by magnetic resonance spectroscopy in patients with bipolar disorder: a meta …

Schizophrenia is associated with significant cognitive impairment. Bipolar disorder (BD) also
presents with cognitive deficits that are similar to, albeit less severe, than those reported in …

Objectives To identify triggers of acute mood episodes in bipolar disorder (BD). Methods We
performed a systematic review in the following databases: Pubmed, Embase, and PsycInfo …