Background Working memory decline has been associated with normal aging. The frontal
brain structure responsible for this decline is primarily located in the prefrontal cortex (PFC) …

Prior randomized control trials have shown that cognitive training interventions resulted in
improved proximal task performance, improved functioning of activities of daily living, and …

Minimizing head motion during functional magnetic resonance imaging (fMRI) is important
for maintaining the integrity of neuroimaging data. While there are a variety of techniques to …

Objective: This study examines the impact of transcranial direct current stimulation (tDCS)
combined with cognitive training on neurotransmitter concentrations in the prefrontal cortex …

Objective: Processing speed (PS) is an important indicator of cognitive functioning and
normal aging. However, the tools used to evaluate these are often rather simplistic and only …

Background Ketamine has become a major substance of abuse worldwide. Nevertheless,
The long-term effects of ketamine use on intrinsic spontaneous neural activity remain …

Cognitive training has shown promise for improving cognition in older adults. Age-related
neuroanatomical changes may affect cognitive training outcomes. White matter …

Speed-of-processing abilities decline with age yet are important in performing instrumental
activities of daily living. The useful field of view, or Double Decision task, assesses speed-of …

Declines in several cognitive domains, most notably processing speed, occur in non-
pathological aging. Given the exponential growth of the older adult population, declines in …

Cognitive training using a visual speed-of-processing task, called the Useful Field of View
(UFOV) task, reduced dementia risk and reduced decline in activities of daily living at a 10 …