Vascular cognitive impairment (VCI) is a lifelong process encompassing a broad spectrum of
cognitive disorders, ranging from subtle or mild deficits to prodromal and fully developed …

White matter hyperintensities (WMHs) of presumed vascular origin are one of the imaging
markers of cerebral small-vessel disease, which is prevalent in older individuals and closely …

Purpose We developed an end‐to‐end workflow that starts with a vendor‐neutral acquisition
and tested the hypothesis that vendor‐neutral sequences decrease inter‐vendor variability …

Introduction Arterial stiffness may play a role in the development of dementia through poorly
understood effects on brain microstructural integrity and perfusion. Methods We examined …

Background Arterial stiffness leads to several adverse events in the older population, but
there is a lack of data on its association with frailty, disability, and mortality in the same …

Objective The role of vascular risk factors in age‐related brain degeneration has long been
the subject of intense study, but the role of obesity remains understudied. Given known sex …

Cardiovascular ageing contributes to cognitive impairment. However, the unique and
synergistic contributions of multiple cardiovascular factors to cognitive function remain …

Background Pulse‐wave velocity is a measure of arterial stiffness and a risk factor for
cardiovascular disease. Recently, an estimated pulse‐wave velocity (ePWV) was introduced …

Background: Vascular risk factors such as arterial stiffness play an important role in the
etiology of Alzheimer's disease (AD), presumably due to the emergence of white matter …

This chapter provides a synthesis of the literature linking sleep disturbance to dementia and
mild cognitive impairment (MCI), a key 'at-risk'stage for dementia. It firstly outlines dementia …