I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally
divided into two main phenotypic subsets, based on the presence of nasal polyps …

Background ANDHI was done to assess the efficacy of benralizumab, including onset of
effect and impact on health-related quality of life (HRQOL), exacerbation rate, lung function …

Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) negatively affects health‐
related quality of life (HRQoL). In a previously reported randomized clinical trial …

Background Clinically meaningful improvement in the Sino‐Nasal Outcome Test‐22 (SNOT‐
22) was observed in patients with severe, eosinophilic asthma, and nasal polyposis (NP) …

Objective: The large amount of evidence and the renewed interest in upper and lower
airways involvement in infectious and inflammatory diseases has led Interasma (Global …

Nasal mucosa injury can be caused by trauma, radiotherapy, chronic infection such as
sinusitis, and post sinus surgery. The rate of healing and its treatment are important in the …

Purpose Budesonide improves the prognosis of chronic rhinosinusitis (CRS). However, few
reports have examined whether its use for nasal irrigation, compared to normal saline …

This review describes beneficial effects and adverse events of various intranasal
medications in treating rhinosinusitis. Application of intranasal steroids has been described …

Objectives We conducted a systematic literature review (SLR) of randomized controlled trials
and real-world evidence (RWE) studies to determine the humanistic (eg health …