1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Vitamin D, the sunshine vitamin, has received a lot of attention recently as a result of a
meteoric rise in the number of publications showing that vitamin D plays a crucial role in a …

Abstract Introduction: Adequate Vitamin D intake and its concentration in serum are
important for bone health and calcium–phosphate metabolism as well as for optimal function …

Objective To evaluate the breadth, validity, and presence of biases of the associations of
vitamin D with diverse outcomes. Design Umbrella review of the evidence across systematic …

Introduction: Vitamin D has been primarily studied as an important factor influencing bone
and calcium metabolism. Metabolites of vitamin D are essential for whole-body calcium …

Vitamin D plays a classical hormonal role in skeletal health by regulating calcium and
phosphorus metabolism. Vitamin D metabolites also have physiological functions in …

Cardiovascular disease (CVD) follows a seasonal pattern in many populations. Broadly
defined winter peaks and clusters of all subtypes of CVD after'cold snaps' are consistently …

Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …

Dietary supplements are widely used and offer the potential to improve health if
appropriately targeted to those in need. Inadequate nutrition and micronutrient deficiencies …

The evidence on the association between baseline vitamin D status and risk of incident
hypertension in general populations is limited and has not been reliably quantified. We …