[HTML][HTML] Implementing CRISPR-Cas technologies in conventional and non-conventional yeasts: Current state and future prospects

H Raschmanová, A Weninger, A Glieder, K Kovar… - Biotechnology …, 2018 - Elsevier
Within five years, the CRISPR-Cas system has emerged as the dominating tool for genome
engineering, while also changing the speed and efficiency of metabolic engineering in …

[PDF][PDF] Candida albicans: genetics, dimorphism and pathogenicity

G Molero, R Diez-Orejas, F Navarro-Garcia… - International …, 1998 - researchgate.net
Candida albicans is a dimorphic fungus that causes severe opportunistic infections in
humans. Recent advances in molecular biology techniques applied to this organism …

Rapid Hypothesis Testing with Candida albicans through Gene Disruption with Short Homology Regions

RB Wilson, D Davis, AP Mitchell - Journal of bacteriology, 1999 - Am Soc Microbiol
Disruption of newly identified genes in the pathogen Candida albicans is a vital step in
determination of gene function. Several gene disruption methods described previously …

Strains and Strategies for Large-Scale Gene Deletion Studies of the Diploid Human Fungal Pathogen Candida albicans

SM Noble, AD Johnson - Eukaryotic cell, 2005 - Am Soc Microbiol
Candida albicans is the most common human fungal pathogen and causes significant
morbidity and mortality worldwide. Nevertheless, the basic principles of C. albicans …

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

IV Ene, AK Adya, S Wehmeier, AC Brand… - Cellular …, 2012 - Wiley Online Library
The survival of all microbes depends upon their ability to respond to environmental
challenges. To establish infection, pathogens such as C andida albicans must mount …

From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral …

B Wächtler, D Wilson, K Haedicke, F Dalle, B Hube - PloS one, 2011 - journals.plos.org
Candida albicans frequently causes superficial infections by invading and damaging
epithelial cells, but may also cause systemic infections by penetrating through epithelial …

Induction of Mating in Candida albicans by Construction of MTLa and MTLα Strains

BB Magee, PT Magee - Science, 2000 - science.org
Although the diploid fungus Candida albicans, a human pathogen, has been thought to
have no sexual cycle, it normally possesses mating-type–like orthologs (MTL) of both of the …

Role of the Mitogen-Activated Protein Kinase Hog1p in Morphogenesis and Virulence of Candida albicans

R Alonso-Monge, F Navarro-Garcia… - Journal of …, 1999 - Am Soc Microbiol
The relevance of the mitogen-activated protein (MAP) kinase Hog1p in Candida albicans
was addressed through the characterization of C. albicans strains without a functional HOG1 …

Superoxide Dismutases in Candida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-induced SOD5 Gene

M Martchenko, AM Alarco, D Harcus… - Molecular biology of …, 2004 - Am Soc Cell Biol
Superoxide dismutases (SOD) convert superoxide radicals into less damaging hydrogen
peroxide. The opportunistic human pathogen Candida albicans is known to express …

The Hog1 Mitogen-Activated Protein Kinase Is Essential in the Oxidative Stress Response and Chlamydospore Formation in Candidaalbicans

R Alonso-Monge, F Navarro-García, E Román… - Eukaryotic …, 2003 - Am Soc Microbiol
Candida albicans mutants with mutations in mitogen-activated protein (MAP) kinase HOG1
displayed an increased sensitivity to agents producing reactive oxygen species, such as …