The proteasome system is a large and complex molecular machinery responsible for the
degradation of misfolded, damaged, and redundant cellular proteins. When proteasome …

Many heterocyclic compounds can be synthetized using diaza-1, 3-butadienes (DADs) as
key structural precursors. Isolated and in situ diaza-1, 3-butadienes, produced from their …

Chiral imidazolidine shows its potential in multiple fields. However, direct catalytic
asymmetric construction of chiral imidazolidines is still limited. Herein, we report an effective …

Ionic liquids (ILs) possess a broad spectrum and cutting-edge impact on promising and
sustainable research works due to their utilization in academic as well as industrial …

Aim: A novel series of fused benzochromenes with expected cytotoxicity and HIF-1α
inhibition was identified. Materials & methods: A bioisosterism-aided approach was applied …

The tripodal compounds [(TMG3trphen) MII–solv](PF6) 2 (M= Mn, Fe, Co; solv= MeCN, DMF)
and bipodal analogues [(TMG2biphen) MII (NCMe) x](PF6) 2 (x= 3 for Mn, Fe; x= 2 for Co) …

Chiral 2-substituted imidazolines are not only privileged scaffolds in many bioactive
compounds, but they are also widely used as ligands and catalysts in asymmetric synthesis …

A straightforward strategy toward the efficient synthesis of linear saturated polyamines
containing 1, 2-diaminoethane and/or 1, 3-diaminopropane fragments has been developed …

An electrochemical tandem radical trifluoromethylation of allylamines/formal (3+ 2)-
cycloaddition with nitrile and carbonyl compounds has been developed under mild and …

A systematized survey of reviews and monographs published in 2021 on all aspects of
heterocyclic chemistry is given. Methods for the synthesis, reactivity, and practically useful …