Muscle stem cell quiescence: controlling stemness by staying asleep

S Ancel, P Stuelsatz, JN Feige - Trends in Cell Biology, 2021 - cell.com
Muscle stem cells (MuSCs) are tissue-resident stem cells required for growth and repair of
skeletal muscle, that are otherwise maintained in a cell-cycle-arrested state called …

[HTML][HTML] Human and mouse skeletal muscle stem and progenitor cells in health and disease

B Mierzejewski, K Archacka, I Grabowska… - Seminars in cell & …, 2020 - Elsevier
The proper functioning of tissues and organs depends on their ability to self-renew and
repair. Some of the tissues, like epithelia, renew almost constantly while in the others this …

[HTML][HTML] Muscle stem/progenitor cells and mesenchymal stem cells of bone marrow origin for skeletal muscle regeneration in muscular dystrophies

A Klimczak, U Kozlowska, M Kurpisz - Archivum immunologiae et …, 2018 - Springer
Muscular dystrophies represent a group of diseases which may develop in several forms,
and severity of the disease is usually associated with gene mutations. In skeletal muscle …

iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

D Guo, K Daman, JJC Chen, MJ Shi, J Yan… - Elife, 2022 - elifesciences.org
Skeletal muscle myoblasts (iMyoblasts) were generated from human induced pluripotent
stem cells (iPSCs) using an efficient and reliable transgene-free induction and stem cell …

Reconstruction of muscle fascicle‐like tissues by anisotropic 3D patterning

Y Jin, EJ Jeon, S Jeong, S Min, YS Choi… - Advanced Functional …, 2021 - Wiley Online Library
Tissue engineering of skeletal muscle has been proposed as a potential regenerative
treatment for extensive muscle damage. In this regard, the highly organized structure of …

Myoblast deactivation within engineered human skeletal muscle creates a transcriptionally heterogeneous population of quiescent satellite-like cells

J Wang, T Broer, T Chavez, CJ Zhou, S Tran, Y Xiang… - Biomaterials, 2022 - Elsevier
Satellite cells (SCs), the adult Pax7-expressing stem cells of skeletal muscle, are essential
for muscle repair. However, in vitro investigations of SC function are challenging due to …

[PDF][PDF] Activating a reserve neural stem cell population in vitro enables engraftment and multipotency after transplantation

J Peterson, B Lin, CM Barrios-Camacho, DB Herrick… - Stem Cell Reports, 2019 - cell.com
The olfactory epithelium (OE) regenerates after injury via two types of tissue stem cells:
active globose cells (GBCs) and dormant horizontal basal cells (HBCs). HBCs are roused to …

[HTML][HTML] Muscle stem cell-derived extracellular vesicles reverse hydrogen peroxide-induced mitochondrial dysfunction in mouse myotubes

KT Shuler, BE Wilson, ER Muñoz, AD Mitchell… - Cells, 2020 - mdpi.com
Muscle stem cells (MuSCs) hold great potential as a regenerative therapeutic but have met
numerous challenges in treating systemic muscle diseases. Muscle stem cell-derived …

[HTML][HTML] Generation of human myogenic progenitors from pluripotent stem cells for in vivo regeneration

H Kim, RCR Perlingeiro - Cellular and Molecular Life Sciences, 2022 - Springer
Muscular dystrophy encompasses a large number of heterogeneous genetic disorders
characterized by progressive and devastating muscle wasting. Cell-based replacement …

[HTML][HTML] A novel PAX7 10-bp indel variant modulates promoter activity, gene expression and contributes to different phenotypes of Chinese cattle

Y Xu, T Shi, Y Zhou, M Liu, S Klaus, X Lan, C Lei… - Scientific reports, 2018 - nature.com
Abstract Paired box 7 (PAX7) gene regulates the conversion of muscle satellite cells into
myogenic cells and participates in multi-step processes in myogenesis. Expression levels of …