[HTML][HTML] Control of mammalian locomotion by somatosensory feedback

A Frigon, T Akay, BI Prilutsky - Comprehensive physiology, 2021 - ncbi.nlm.nih.gov
When animals walk overground, mechanical stimuli activate various receptors located in
muscles, joints and skin. Afferents from these mechanoreceptors project to neuronal …

Distribution of motor unit properties across human muscles

J Duchateau, RM Enoka - Journal of Applied Physiology, 2022 - journals.physiology.org
The purpose of our review was to compare the distribution of motor unit properties across
human muscles of different sizes and recruitment ranges. Although motor units can be …

[HTML][HTML] A cellular taxonomy of the adult human spinal cord

A Yadav, KJE Matson, L Li, I Hua, J Petrescu, K Kang… - Neuron, 2023 - cell.com
The mammalian spinal cord functions as a community of cell types for sensory processing,
autonomic control, and movement. While animal models have advanced our understanding …

[PDF][PDF] Tools for comprehensive reconstruction and analysis of Drosophila motor circuits

A Azevedo, E Lesser, B Mark, J Phelps, L Elabbady… - BioRxiv, 2022 - scholar.archive.org
Like the vertebrate spinal cord, the insect ventral nerve cord (VNC) mediates limb sensation
and motor control. Here, we applied automated tools for electron microscopy (EM) volume …

Estimates of persistent inward currents increase with the level of voluntary drive in low-threshold motor units of plantar flexor muscles

LBR Orssatto, K Mackay, AJ Shield… - Journal of …, 2021 - journals.physiology.org
This study tested whether estimates of persistent inward currents (PICs) in the human
plantar flexors would increase with the level of voluntary drive. High-density surface …

Estimation of the firing behaviour of a complete motoneuron pool by combining electromyography signal decomposition and realistic motoneuron modelling

AH Caillet, ATM Phillips, D Farina… - PLOS Computational …, 2022 - journals.plos.org
Our understanding of the firing behaviour of motoneuron (MN) pools during human voluntary
muscle contractions is currently limited to electrophysiological findings from animal …

Myomatrix arrays for high-definition muscle recording

B Chung, M Zia, KA Thomas, JA Michaels, A Jacob… - Elife, 2023 - elifesciences.org
Neurons coordinate their activity to produce an astonishing variety of motor behaviors. Our
present understanding of motor control has grown rapidly thanks to new methods for …

Aging affects the number and morphological heterogeneity of rat phrenic motor neurons and phrenic motor axons

MJ Fogarty, GC Sieck - Physiological Reports, 2023 - Wiley Online Library
Diaphragm muscle (DIAm) motor units comprise a phrenic motor neuron (PhMN), the
phrenic nerve and the muscle fibers innervated, with the size of PhMNs and axons …

Motoneuron-driven computational muscle modelling with motor unit resolution and subject-specific musculoskeletal anatomy

AH Caillet, ATM Phillips, D Farina… - PLOS Computational …, 2023 - journals.plos.org
The computational simulation of human voluntary muscle contraction is possible with EMG-
driven Hill-type models of whole muscles. Despite impactful applications in numerous fields …

Chemogenetic inhibition of TrkB signalling reduces phrenic motor neuron survival and size

MJ Fogarty, D Dasgupta, OU Khurram… - Molecular and Cellular …, 2023 - Elsevier
Brain derived neurotrophic factor (BDNF) signalling through its high-affinity tropomyosin
receptor kinase B (TrkB) is known to have potent effects on motor neuron survival and …