Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells
Membrane contact sites between organelles are essential for maintaining cellular
homeostasis, which requires the continuous exchange of signaling molecules, ions …
homeostasis, which requires the continuous exchange of signaling molecules, ions …
Hijacking cellular stress responses to promote lifespan
N Dutta, G Garcia, R Higuchi-Sanabria - Frontiers in Aging, 2022 - frontiersin.org
Organisms are constantly exposed to stress both from the external environment and
internally within the cell. To maintain cellular homeostasis under different environmental and …
internally within the cell. To maintain cellular homeostasis under different environmental and …
The key role of proteostasis at mitochondria-associated endoplasmic reticulum membrane in vanadium-induced nephrotoxicity using a proteomic strategy
X Wang, C Xing, G Li, X Dai, X Gao, Y Zhuang… - Science of The Total …, 2023 - Elsevier
Excessive vanadium (V) contamination is an attracting growing concern, which can
negatively affect the health of human and ecosystems. But how V causes nephrotoxicity and …
negatively affect the health of human and ecosystems. But how V causes nephrotoxicity and …
The aging of ER-mitochondria communication: A journey from undifferentiated to aged cells
P Morgado-Cáceres, G Liabeuf, X Calle… - Frontiers in Cell and …, 2022 - frontiersin.org
The complex physiology of eukaryotic cells requires that a variety of subcellular organelles
perform unique tasks, even though they form highly dynamic communication networks. In the …
perform unique tasks, even though they form highly dynamic communication networks. In the …
Methods for assessing change in brain plasticity at night and psychological resilience during daytime between repeated long-duration space missions
K Otsuka, G Cornelissen, Y Kubo, K Shibata… - Scientific reports, 2023 - nature.com
This study was designed to examine the feasibility of analyzing heart rate variability (HRV)
data from repeat-flier astronauts at matching days on two separate missions to assess any …
data from repeat-flier astronauts at matching days on two separate missions to assess any …
Single image capture of bioactive ion crosstalk within inter‐organelle membrane contacts at nanometer resolution
G Fang, H Chen, X Shao, H Wang, D Zhan… - Small …, 2022 - Wiley Online Library
Rapid bioactive ion exchange is a form of communication that regulates a wide range of
biological processes. Despite advances in super‐resolution optical microscopy, visualizing …
biological processes. Despite advances in super‐resolution optical microscopy, visualizing …
Mitoribosomal synthetic lethality overcomes multidrug resistance in MYC-driven neuroblastoma
K Borankova, M Krchniakova, LYW Leck… - Cell Death & …, 2023 - nature.com
Mitochondria are central for cancer responses to therapy-induced stress signals. Refractory
tumors often show attenuated sensitivity to apoptotic signaling, yet clinically relevant …
tumors often show attenuated sensitivity to apoptotic signaling, yet clinically relevant …
IP3R at ER-Mitochondrial Contact Sites: Beyond the IP3R-GRP75-VDAC1 Ca2+ Funnel
P Atakpa-Adaji, A Ivanova - Contact, 2023 - journals.sagepub.com
Membrane contact sites (MCS) circumvent the topological constraints of functional coupling
between different membrane-bound organelles by providing a means of communication and …
between different membrane-bound organelles by providing a means of communication and …
Enhancing healthy aging with small molecules: A mitochondrial perspective
X Qin, H Li, H Zhao, L Fang… - Medicinal Research …, 2024 - Wiley Online Library
The pursuit of enhanced health during aging has prompted the exploration of various
strategies focused on reducing the decline associated with the aging process. A key area of …
strategies focused on reducing the decline associated with the aging process. A key area of …
TRAP1 in oxidative stress and neurodegeneration
I Ramos Rego, B Santos Cruz, AF Ambrósio, CH Alves - Antioxidants, 2021 - mdpi.com
Tumor necrosis factor receptor-associated protein 1 (TRAP1), also known as heat shock
protein 75 (HSP75), is a member of the heat shock protein 90 (HSP90) chaperone family …
protein 75 (HSP75), is a member of the heat shock protein 90 (HSP90) chaperone family …