Recent advances in biosensor technology for potential applications–an overview

S Vigneshvar, CC Sudhakumari… - … in bioengineering and …, 2016 - frontiersin.org
Imperative utilization of biosensors has acquired paramount importance in the field of drug
discovery, biomedicine, food safety standards, defense, security, and environmental …

The role of mitochondria in axon development and regeneration

GM Smith, G Gallo - Developmental neurobiology, 2018 - Wiley Online Library
Mitochondria are dynamic organelles that undergo transport, fission, and fusion. The three
main functions of mitochondria are to generate ATP, buffer cytosolic calcium, and generate …

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

NMC Connolly, P Theurey, V Adam-Vizi… - Cell Death & …, 2018 - nature.com
Neurodegenerative diseases are a spectrum of chronic, debilitating disorders characterised
by the progressive degeneration and death of neurons. Mitochondrial dysfunction has been …

Mitochondria as the target of hepatotoxicity and drug-induced liver injury: molecular mechanisms and detection methods

M Mihajlovic, M Vinken - International journal of molecular sciences, 2022 - mdpi.com
One of the major mechanisms of drug-induced liver injury includes mitochondrial
perturbation and dysfunction. This is not a surprise, given that mitochondria are essential …

ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology

V De Col, P Fuchs, T Nietzel, M Elsässer, CP Voon… - Elife, 2017 - elifesciences.org
Growth and development of plants is ultimately driven by light energy captured through
photosynthesis. ATP acts as universal cellular energy cofactor fuelling all life processes …

Bridging the gap between in vitro and in vivo RNA folding

KA Leamy, SM Assmann, DH Mathews… - Quarterly reviews of …, 2016 - cambridge.org
Deciphering the folding pathways and predicting the structures of complex three-
dimensional biomolecules is central to elucidating biological function. RNA is single …

Visualizing mitochondrial form and function within the cell

B Glancy - Trends in molecular medicine, 2020 - cell.com
The specific cellular role of mitochondria is influenced by the surrounding environment
because effective mitochondrial function requires the delivery of inputs (eg, oxygen) and …

Recent advances in the potential applications of luminescence-based, SPR-based, and carbon-based biosensors

U Anand, AKS Chandel, P Oleksak, A Mishra… - Applied Microbiology …, 2022 - Springer
The need for biosensors has evolved in the detection of molecules, diseases, and pollution
from various sources. This requirement has headed to the development of accurate and …

High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions

AC Little, I Kovalenko, LE Goo, HS Hong… - Communications …, 2020 - nature.com
Metabolic flux technology with the Seahorse bioanalyzer has emerged as a standard
technique in cellular metabolism studies, allowing for simultaneous kinetic measurements of …

A ratiometric two-photon probe for quantitative imaging of mitochondrial pH values

AR Sarkar, CH Heo, L Xu, HW Lee, HY Si, JW Byun… - Chemical …, 2016 - pubs.rsc.org
Mitochondrial pH (pHmito) is known to be alkaline (near 8.0) and has emerged as a
potential factor for mitochondrial function and disorder. We have developed a ratiometric two …