Distinguishing string selection problems
This paper presents a collection of string algorithms that are at the core of several biological
problems such as discovering potential drug targets, creating diagnostic probes, universal …
problems such as discovering potential drug targets, creating diagnostic probes, universal …
On the closest string and substring problems
The problem of finding a center string that is" close" to every given string arises in
computational molecular biology and coding theory. This problem has two versions: the …
computational molecular biology and coding theory. This problem has two versions: the …
Fixed-parameter algorithms for closest string and related problems
Gramm, Niedermeier, Rossmanith - Algorithmica, 2003 - Springer
CLOSEST STRING is one of the core problems in the field of consensus word analysis with
particular importance for computational biology. Given k strings of the same length and a …
particular importance for computational biology. Given k strings of the same length and a …
[PDF][PDF] Finding similar regions in many strings
Algorithms for finding similar, or highly conserved, regions in a group of sequences are at
the core of many molecular biology problems. We solve three main open questions in this …
the core of many molecular biology problems. We solve three main open questions in this …
[HTML][HTML] The consensus string problem for a metric is NP-complete
JS Sim, K Park - Journal of Discrete Algorithms, 2003 - Elsevier
Given a set S of strings, a consensus string of S based on consensus error is a string w that
minimizes the sum of the distances between w and all the strings in S. In this paper, we …
minimizes the sum of the distances between w and all the strings in S. In this paper, we …
[PDF][PDF] Some results on approximating the minimax solution in approval voting.
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r5 8H g HPT0r $ T0HPT3f a3Tt bdp8h pdHPT3p" b FPC § fu C § f (R c § FPChxb8p8T3f FD …
r5 8H g HPT0r $ T0HPT3f a3Tt bdp8h pdHPT3p" b FPC § fu C § f (R c § FPChxb8p8T3f FD …
Optimal solutions for the closest-string problem via integer programming
In this paper we study the closest-string problem (CSP), which can be defined as follows:
Given a finite set 𝒮={s1, s2,…, sn} of strings, each string with length m, find a center string t …
Given a finite set 𝒮={s1, s2,…, sn} of strings, each string with length m, find a center string t …
On the parameterized intractability of motif search problems
MR Fellows, J Gramm, R Niedermeier - Combinatorica, 2006 - Springer
We show that Closest Substring, one of the most important problems in the field of
consensus string analysis, is W [1]-hard when parameterized by the number k of input …
consensus string analysis, is W [1]-hard when parameterized by the number k of input …
Optimization techniques for string selection and comparison problems in genomics
CN Meneses, CAS Oliveira… - IEEE Engineering in …, 2005 - ieeexplore.ieee.org
In this article, a discussion of optimization issues occurring in the area of genomics such as
string comparison and selection problems are discussed. With this objective, an important …
string comparison and selection problems are discussed. With this objective, an important …
Explaining and controlling ambiguity in dynamic programming
R Giegerich - Annual Symposium on Combinatorial Pattern Matching, 2000 - Springer
Ambiguity in dynamic programming arises from two independent sources, the non-
uniqueness of optimal solutions and the particular recursion scheme by which the search …
uniqueness of optimal solutions and the particular recursion scheme by which the search …