[HTML][HTML] What is plan quality in radiotherapy? The importance of evaluating dose metrics, complexity, and robustness of treatment plans

V Hernandez, CR Hansen, L Widesott, A Bäck… - Radiotherapy and …, 2020 - Elsevier
Plan evaluation is a key step in the radiotherapy treatment workflow. Central to this step is
the assessment of treatment plan quality. Hence, it is important to agree on what we mean …

Clinical application of MR-Linac in tumor radiotherapy: a systematic review

X Liu, Z Li, Y Yin - Radiation Oncology, 2023 - Springer
Recent years have seen both a fresh knowledge of cancer and impressive advancements in
its treatment. However, the clinical treatment paradigm of cancer is still difficult to implement …

Comparing different CT, PET and MRI multi-modality image combinations for deep learning-based head and neck tumor segmentation

J Ren, JG Eriksen, J Nijkamp, SS Korreman - Acta Oncologica, 2021 - Taylor & Francis
Background Manual delineation of gross tumor volume (GTV) is essential for radiotherapy
treatment planning, but it is time-consuming and suffers inter-observer variability (IOV). In …

[HTML][HTML] Evaluation of decentralised model-based selection of head and neck cancer patients for a proton treatment study. DAHANCA 35

CR Hansen, K Jensen, B Smulders, AIS Holm… - Radiotherapy and …, 2024 - Elsevier
Introduction Proton treatment can potentially spare patients with H&N cancer for substantial
treatment-related toxicities. The current study investigated the reproducibility of a …

Head and neck cancer patients under (chemo-) radiotherapy undergoing nutritional intervention: Results from the prospective randomized HEADNUT-trial

A Löser, J Abel, LM Kutz, L Krause, A Finger… - Radiotherapy and …, 2021 - Elsevier
Purpose/objective Patients with squamous cell carcinoma of the head and neck undergoing
(chemo-) radiotherapy are at high risk of malnutrition. Nevertheless, there is still a lack of …

[HTML][HTML] The use of MR-guided radiation therapy for head and neck cancer and recommended reporting guidance

BA McDonald, R Dal Bello, CD Fuller… - Seminars in radiation …, 2024 - Elsevier
Although magnetic resonance imaging (MRI) has become standard diagnostic workup for
head and neck malignancies and is currently recommended by most radiological societies …

Re-irradiation for head and neck cancer: cumulative dose to organs at risk and late side effects

A Embring, E Onjukka, C Mercke, I Lax, A Berglund… - Cancers, 2021 - mdpi.com
Simple Summary Local recurrences of head and neck cancer are unfortunately common and
can be difficult to treat. The treatment is challenging, partly due to the location, with several …

[HTML][HTML] Considerations for study design in the DAHANCA 35 trial of protons versus photons for head and neck cancer

J Friborg, K Jensen, JG Eriksen, E Samsøe… - Radiotherapy and …, 2023 - Elsevier
Proton radiotherapy offers a dosimetric advantage compared to photon therapy in sparing
normal tissue, but the clinical evidence for toxicity reductions in the treatment of head and …

Plan quality in radiotherapy treatment planning–Review of the factors and challenges

CR Hansen, M Hussein, U Bernchou… - Journal of Medical …, 2022 - Wiley Online Library
A high‐quality treatment plan aims to best achieve the clinical prescription, balancing high
target dose to maximise tumour control against sufficiently low organ‐at‐risk dose for …

Treatment outcomes and survival following definitive (chemo) radiotherapy in HPV‐positive oropharynx cancer: Large‐scale comparison of DAHANCA vs PMH …

P Lassen, SH Huang, J Su, J Waldron… - … Journal of Cancer, 2022 - Wiley Online Library
We compare outcomes in two large‐scale contemporaneously treated HPV‐positive (HPV+)
oropharynx cancer (OPC) cohorts treated with definitive radiotherapy/chemoradiotherapy …