[HTML][HTML] Antibody therapeutics as interfering agents in flow cytometry crossmatch for organ transplantation
Donor–recipient matching is a highly individualized and complex component of solid organ
transplantation. Flowcytometry crossmatching (FC-XM) is an integral step in the matching …
transplantation. Flowcytometry crossmatching (FC-XM) is an integral step in the matching …
Improved flow cytometry crossmatching in kidney transplantation
N Guillaume - Hla, 2018 - Wiley Online Library
Flow cytometry crossmatching (FC‐XM) assay is the most sensitive cell‐based method for
detecting donor‐specific antibodies (DSAs). However, the use of FC‐XM remains limited by …
detecting donor‐specific antibodies (DSAs). However, the use of FC‐XM remains limited by …
Modified flow cytometry crossmatch detecting alloantibody-related cytotoxicity as a way to distinguish lytic antibodies from harmless in allosensitised kidney recipients
M Zieliński, H Zielińska, G Moszkowska… - Transplantation …, 2013 - Elsevier
The serological complement-dependent cytotoxicity crossmatch (CDC-XM) permits routine
identification of anti-donor alloantibodies in the sera of allotransplant recipients. However, in …
identification of anti-donor alloantibodies in the sera of allotransplant recipients. However, in …
Improved flow cytometry based cytotoxicity and binding assay for clinical antibody HLA crossmatching
M Alheim, PK Paul, DM Hauzenberger, AC Wikström - Human Immunology, 2015 - Elsevier
The presence of preformed donor-specific HLA antibodies leads to early antibody mediated
kidney allograft rejection. Therefore, detection and avoidance of donor reactive HLA …
kidney allograft rejection. Therefore, detection and avoidance of donor reactive HLA …
Cytotoxic antibody detection by means of flow-cytometric cross-match
T Bilgen, P Ata, J Tozkir, H Tozkir, MI Titiz - Transplantation proceedings, 2017 - Elsevier
Background Complement-dependent lymphocytotoxicity (CDC-XM) and flow-cytometric
(FCXM) cross-match are analyzed individually for each donor and recipient pair, because …
(FCXM) cross-match are analyzed individually for each donor and recipient pair, because …
Evaluation of a new flow cytometry crossmatch procedure for simultaneous detection of cytotoxicity and antibody binding
M Alheim, PK Paul, DM Hauzenberger… - Tissue …, 2013 - Wiley Online Library
In this study we have evaluated an alternative 96‐well format flow cytometry based (FCtox)
method which enable simultaneous detection of cytotoxicity and human leukocyte antigen …
method which enable simultaneous detection of cytotoxicity and human leukocyte antigen …
For anti-HLA-specific donor antibodies detection by flow cytometry cytotoxic crossmatches comparison of methods
C Cervelli, F Pisani, A Aureli, R Azzarone… - Transplantation …, 2013 - Elsevier
Anti-HLA-specific donor antibodies induce rapid, irreversible destruction of the transplant
(hyperacute rejection) that today happens rarely due to immunologic studies—prospective …
(hyperacute rejection) that today happens rarely due to immunologic studies—prospective …
Comparison of cytotoxic flow cytometric cross match with complement dependent lymphocytotoxicity and flow cytometric cross match in renal transplant patients
T Bilgen, M Canbakan, G Şahin, Mİ Titiz - Transplantation Proceedings, 2019 - Elsevier
Cytotoxic flow cytometric crossmatch (cFCXM), identified by detecting complement-mediated
cytotoxic cell death in addition to the capability of showing the alloantibodies binding onto …
cytotoxic cell death in addition to the capability of showing the alloantibodies binding onto …
The utility of cytolytic flow cytometry crossmatch before kidney transplantation
G Moszkowska, H Zielińska, M Zieliński… - Transplant …, 2021 - Elsevier
The donor/recipient matching in kidney transplantation is based on approved laboratory
tests, which are complement-dependent cytotoxic crossmatch (CDC-XM) and flow cytometry …
tests, which are complement-dependent cytotoxic crossmatch (CDC-XM) and flow cytometry …
Association of C1q Binding Status With De Novo HLA Antibody Clinical Features and Allograft Function in Kidney Transplantation Patients During Eight Years of …
X Wei, X Yuan, M Sun, Z Pan, L Hu, L Wang… - Transplantation …, 2016 - Elsevier
Background C1q-binding donor-specific antibody (DSA) is detrimental to transplanted
kidney function. However, the factors that affect C1q binding status are unclear. Methods A …
kidney function. However, the factors that affect C1q binding status are unclear. Methods A …