The role of β-adrenergic receptors (βARs) in adipose tissue to promote lipolysis and the
release of fatty acids and nonshivering thermogenesis in brown fat has been studied for so …

Beiging of white adipose tissue (WAT) is associated with an increase of anti-inflammatory
M2-like macrophages in WAT. However, mechanisms through which M2-like macrophages …

Abstract p62 (also known as SQSTM1) is widely used as a predictor of autophagic flux, a
process that allows the degradation of harmful and unnecessary components through …

Abstract Pyruvate kinase M2 (PKM2), a glycolytic rate-limiting enzyme, reportedly plays an
important role in tumorigenesis and the inflammatory response by regulating the metabolic …

Mammalian adipose tissue can be divided into white and brown adipose tissue based on its
colour, location, and cellular structure. Certain conditions, such as sympathetic nerve …

Adipocytes robustly synthesize fatty acids (FA) from carbohydrate through the de novo
lipogenesis (DNL) pathway, yet surprisingly DNL contributes little to their abundant …

Type 2 diabetes mellitus (T2DM) is a chronic disease that has become a global public health
problem. Studies on T2DM prevention and treatment mostly focus on discovering …

Background Thyroid cancer is one of the most common endocrine malignancies worldwide,
and papillary thyroid cancer (PTC) is the most common pathologic type of thyroid cancer …

Background Alcohol-associated liver disease (ALD) is a worldwide health problem, of which
the effective treatment is still lacking. Both detrimental and protective roles of adipose tissue …

Brown adipose tissue (BAT) thermogenesis affects energy balance, and thereby it has the
potential to induce weight loss and to prevent obesity. Here, we document a …