Approaches to achieve high‐level heterologous protein production in plants

SJ Streatfield - Plant biotechnology journal, 2007 - Wiley Online Library
Plants offer an alternative to microbial fermentation and animal cell cultures for the
production of recombinant proteins. For protein pharmaceuticals, plant systems are …

Sowing the seeds of success: pharmaceutical proteins from plants

E Stoger, JKC Ma, R Fischer, P Christou - Current opinion in biotechnology, 2005 - Elsevier
Among the many plant-based production systems that have been developed for
pharmaceutical proteins, seeds have the useful advantage of accumulating proteins in a …

The heat shock factor family from Triticum aestivum in response to heat and other major abiotic stresses and their role in regulation of heat shock protein genes

GP Xue, S Sadat, J Drenth… - Journal of experimental …, 2014 - academic.oup.com
Heat shock factors (Hsfs) play a central regulatory role in acquired thermotolerance. To
understand the role of the major molecular players in wheat adaptation to heat stress, the …

TaHsfA6f is a transcriptional activator that regulates a suite of heat stress protection genes in wheat (Triticum aestivum L.) including previously unknown Hsf targets

GP Xue, J Drenth, CL McIntyre - Journal of Experimental Botany, 2015 - academic.oup.com
Heat stress is a significant environmental factor adversely affecting crop yield. Crop
adaptation to high-temperature environments requires transcriptional reprogramming of a …

Green factory: plants as bioproduction platforms for recombinant proteins

J Xu, MC Dolan, G Medrano, CL Cramer… - Biotechnology …, 2012 - Elsevier
Molecular farming, long considered a promising strategy to produce valuable recombinant
proteins not only for human and veterinary medicine, but also for agriculture and industry …

Plant seeds as bioreactors for recombinant protein production

OS Lau, SSM Sun - Biotechnology advances, 2009 - Elsevier
Plants are attractive expression systems for the economic production of recombinant
proteins. Among the different plant-based systems, plant seed is the leading platform and …

Heterologous expression of glycosyl hydrolases in planta: a new departure for biofuels

LE Taylor, Z Dai, SR Decker, R Brunecky… - Trends in …, 2008 - cell.com
The concept of expressing non-plant glycosyl hydrolase genes in plant tissue is nearly two
decades old, yet relatively little work in this field has been reported. However, resurgent …

Commercial cellulosic ethanol: the role of plant-expressed enzymes

MB Sainz - Biofuels: Global Impact on Renewable Energy …, 2011 - Springer
The use and production of biofuels has risen dramatically in recent years Bioethanol
comprises 85% of total global biofuels production, with benefits including reduction of …

Barley genomics: an overview

N Sreenivasulu, A Graner… - International journal of …, 2008 - Wiley Online Library
Barley (Hordeum vulgare), first domesticated in the Near East, is a well‐studied crop in
terms of genetics, genomics, and breeding and qualifies as a model plant for Triticeae …

Genetic engineering of grass cell wall polysaccharides for biorefining

R Bhatia, JA Gallagher, LD Gomez… - Plant Biotechnology …, 2017 - Wiley Online Library
Grasses represent an abundant and widespread source of lignocellulosic biomass, which
has yet to fulfil its potential as a feedstock for biorefining into renewable and sustainable …