Evidence from clinical, preclinical, and post-mortem studies supports the
inflammatory/immune hypothesis of schizophrenia pathogenesis. Less evident is the link …

Background: Inflammation plays a major role in the onset and maintenance of
schizophrenia. The objective of the present work was to synthetize in a narrative review the …

Subclinical inflammation has been associated with psychosis; however, it remains unknown
whether this phenomenon appears also in the premorbid phase. Therefore, we performed a …

Background Patients with schizophrenia display peripheral inflammation but the impact of
illness phase is not clear. Our meta-analysis investigated the difference in CRP levels …

Background and significance. There is a need to develop new hypothesis-driven treatment
for both both major depression (MD) and schizophrenia in which the risk of depression is 5 …

Objectives: The objective of this systematic review was to synthetize the published data on
the relationships between elevated blood C-reactive protein (CRP) levels and schizophrenia …

Objectives: Inflammation, measured by abnormal blood C-reactive protein (CRP) level, has
been described in schizophrenia (SZ), being inconsistently related to impaired cognitive …

Introduction Comorbid depressive symptoms (depression thereafter) often occur in
schizophrenia and are associated with negative outcomes. This meta-analysis estimated the …

Background Studies linking neuro-inflammation to psychotic episodes has been rapidly
expanding. Assessments of changes in inflammatory biomarkers in prodromal patients who …

Objectives Depression and negative symptoms have been associated with impaired Quality
of life (QoL) in schizophrenia (SZ). However, childhood trauma may influence both QoL and …