Glycosylation in health and disease

C Reily, TJ Stewart, MB Renfrow, J Novak - Nature Reviews Nephrology, 2019 - nature.com
The glycome describes the complete repertoire of glycoconjugates composed of
carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules …

[HTML][HTML] Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application

Q Xia, Y Zhang, Z Li, X Hou, N Feng - Acta Pharmaceutica Sinica B, 2019 - Elsevier
Erythrocytes (red blood cells, RBCs) are the most abundant circulating cells in the blood and
have been widely used in drug delivery systems (DDS) because of their features of …

Mucins and the microbiome

GC Hansson - Annual review of biochemistry, 2020 - annualreviews.org
Generating the barriers that protect our inner surfaces from bacteria and other challenges
requires large glycoproteins called mucins. These come in two types, gel-forming and …

Erythrocyte–platelet hybrid membrane coating for enhanced nanoparticle functionalization

D Dehaini, X Wei, RH Fang, S Masson… - Advanced …, 2017 - Wiley Online Library
Cell‐membrane‐coated nanoparticles have recently been studied extensively for their
biological compatibility, retention of cellular properties, and adaptability to a variety of …

Biological roles of glycans

A Varki - Glycobiology, 2017 - academic.oup.com
Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

Mucins: a biologically relevant glycan barrier in mucosal protection

AP Corfield - Biochimica et Biophysica Acta (BBA)-General Subjects, 2015 - Elsevier
Background The mucins found as components of mucus gel layers at mucosal surfaces
throughout the body play roles in protection as part of the defensive barrier on an organ and …

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host–microbial interactions

MEV Johansson, JMH Larsson… - Proceedings of the …, 2011 - National Acad Sciences
The normal intestinal microbiota inhabits the colon mucus without triggering an inflammatory
response. The reason for this and how the intestinal mucus of the colon is organized have …

Multifarious roles of sialic acids in immunity

A Varki, P Gagneux - Annals of the New York Academy of …, 2012 - Wiley Online Library
Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …

Composition and functional role of the mucus layers in the intestine

MEV Johansson, D Ambort, T Pelaseyed… - Cellular and molecular …, 2011 - Springer
In discussions on intestinal protection, the protective capacity of mucus has not been very
much considered. The progress in the last years in understanding the molecular nature of …

[HTML][HTML] Glycosylation in cellular mechanisms of health and disease

K Ohtsubo, JD Marth - cell, 2006 - cell.com
Glycosylation produces an abundant, diverse, and highly regulated repertoire of cellular
glycans that are frequently attached to proteins and lipids. The past decade of research on …