Smart nanoparticles for drug delivery application: development of versatile nanocarrier platforms in biotechnology and nanomedicine

D Lombardo, MA Kiselev… - Journal of …, 2019 - Wiley Online Library
The study of nanostructured drug delivery systems allows the development of novel
platforms for the efficient transport and controlled release of drug molecules in the harsh …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Antibacterial action of nanoparticles by lethal stretching of bacterial cell membranes

DP Linklater, VA Baulin, X Le Guével… - Advanced …, 2020 - Wiley Online Library
It is commonly accepted that nanoparticles (NPs) can kill bacteria; however, the mechanism
of antimicrobial action remains obscure for large NPs that cannot translocate the bacterial …

[HTML][HTML] Recent progress in cryoablation cancer therapy and nanoparticles mediated cryoablation

K Kwak, B Yu, RJ Lewandowski, DH Kim - Theranostics, 2022 - ncbi.nlm.nih.gov
With rapid advances in modern imaging, minimally invasive ablative procedures have
emerged as popular alternatives to surgical removal of tumors. Tumor ablation modalities …

Shape and orientation matter for the cellular uptake of nonspherical particles

S Dasgupta, T Auth, G Gompper - Nano letters, 2014 - ACS Publications
Recent advances in nanotechnology have made a whole zoo of particles of different shapes
available for applications, but their interaction with biological cells and their toxicity is often …

Theoretical and computational investigations of nanoparticle–biomembrane interactions in cellular delivery

H Ding, Y Ma - Small, 2015 - Wiley Online Library
With the rapid development of nanotechnology, nanoparticles have been widely used in
many applications such as phototherapy, cell imaging, and drug/gene delivery. A better …

Effect of particle diameter and surface composition on the spontaneous fusion of monolayer-protected gold nanoparticles with lipid bilayers

RC Van Lehn, PU Atukorale, RP Carney, YS Yang… - Nano …, 2013 - ACS Publications
Anionic, monolayer-protected gold nanoparticles (AuNPs) have been shown to
nondisruptively penetrate cellular membranes. Here, we show that a critical first step in the …

Lipid tail protrusions mediate the insertion of nanoparticles into model cell membranes

RC Van Lehn, M Ricci, PHJ Silva, P Andreozzi… - Nature …, 2014 - nature.com
Recent work has demonstrated that charged gold nanoparticles (AuNPs) protected by an
amphiphilic organic monolayer can spontaneously insert into the core of lipid bilayers to …

Defects and defect engineering in Soft Matter

A Jangizehi, F Schmid, P Besenius, K Kremer… - Soft Matter, 2020 - pubs.rsc.org
Soft matter covers a wide range of materials based on linear or branched polymers, gels and
rubbers, amphiphilic (macro) molecules, colloids, and self-assembled structures. These …

Rational design principles for the transport and subcellular distribution of nanomaterials into plant protoplasts

TTS Lew, MH Wong, SY Kwak, R Sinclair, VB Koman… - Small, 2018 - Wiley Online Library
The ability to control the subcellular localization of nanoparticles within living plants offers
unique advantages for targeted biomolecule delivery and enables important applications in …