Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

Design of biodegradable, implantable devices towards clinical translation

C Li, C Guo, V Fitzpatrick, A Ibrahim… - Nature Reviews …, 2020 - nature.com
Biodegradable materials, including natural and synthetic polymers and hydrolyzable metals,
constitute the main components of temporary, implantable medical devices. Besides the …

Glial responses to implanted electrodes in the brain

JW Salatino, KA Ludwig, TDY Kozai… - Nature biomedical …, 2017 - nature.com
The use of implants that can electrically stimulate or record electrophysiological or
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …

Tissue–electronics interfaces: from implantable devices to engineered tissues

R Feiner, T Dvir - Nature Reviews Materials, 2017 - nature.com
Biomedical electronic devices are interfaced with the human body to extract precise medical
data and to interfere with tissue function by providing electrical stimuli. In this Review, we …

Materials and technologies for soft implantable neuroprostheses

SP Lacour, G Courtine, J Guck - Nature Reviews Materials, 2016 - nature.com
Implantable neuroprostheses are engineered systems designed to restore or substitute
function for individuals with neurological deficits or disabilities. These systems involve at …

Implantable intracortical microelectrodes: reviewing the present with a focus on the future

Y Wang, X Yang, X Zhang, Y Wang… - Microsystems & …, 2023 - nature.com
Implantable intracortical microelectrodes can record a neuron's rapidly changing action
potentials (spikes). In vivo neural activity recording methods often have either high temporal …

Recent advances in nanocellulose for biomedical applications

M Jorfi, EJ Foster - Journal of Applied Polymer Science, 2015 - Wiley Online Library
Nanocellulose materials have undergone rapid development in recent years as promising
biomedical materials because of their excellent physical and biological properties, in …

A bioprinted cardiac patch composed of cardiac‐specific extracellular matrix and progenitor cells for heart repair

D Bejleri, BW Streeter, ALY Nachlas… - Advanced …, 2018 - Wiley Online Library
Congenital heart defects are present in 8 of 1000 newborns and palliative surgical therapy
has increased survival. Despite improved outcomes, many children develop reduced …

Recent progress in materials chemistry to advance flexible bioelectronics in medicine

G Balakrishnan, J Song, C Mou… - Advanced …, 2022 - Wiley Online Library
Designing bioelectronic devices that seamlessly integrate with the human body is a
technological pursuit of great importance. Bioelectronic medical devices that reliably and …

Progress towards biocompatible intracortical microelectrodes for neural interfacing applications

M Jorfi, JL Skousen, C Weder… - Journal of neural …, 2014 - iopscience.iop.org
To ensure long-term consistent neural recordings, next-generation intracortical
microelectrodes are being developed with an increased emphasis on reducing the neuro …