Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Sensitivity and specificity are two most important factors to take into account for molecule
sensing, chemical detection and disease diagnosis. A perfect sensitivity is to reach the level …

Provided herein are methods and devices for characterizing a biomolecule parameter by a
nanopore-containing mem brane, and also methods for making devices that can be used in …

Nanopores can be used to detect and analyse biomolecules. However, controlling the
translocation speed of molecules through a pore is difficult, which limits the wider application …

Nanopore DNA sequencing offers a new paradigm owing to its extensive potential for long-
read, high-throughput detection of nucleotide modification and direct RNA sequencing …

The ingenious design of the bacterial virus phi29 DNA packaging nanomotor with an
elegant and elaborate channel has inspired its application for single molecule detection of …

DNA sequencing methods based on nanopores could potentially represent a low-cost and
high-throughput pathway to practical genomics, by replacing current sequencing methods …

The microscopic details of how peptides translocate one at a time through nanopores are
crucial determinants for transport through membrane pores and important in developing …

Determining the pathological role of amyloids in amyloid-associated diseases will require a
method for characterizing the dynamic distributions in size and shape of amyloid oligomers …

In the 90s, the development of a novel single molecule technique based on nanopore
sensing emerged. Preliminary improvements were based on the molecular or biological …