With heart and cardiovascular diseases continually challenging healthcare systems
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …

Cardiovascular disease is the number one killer worldwide, with myocardial infarction (MI)
responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity …

In the multidisciplinary field of heart research it is of utmost importance to identify accurate
myocardium material properties for the description of phenomena such as mechano-electric …

Soft biological tissues such as aortic walls can be viewed as fibrous composites assembled
by a ground matrix and embedded families of collagen fibres. Changes in the structural …

Arterial walls can be regarded as composite materials consisting of collagen fibers
embedded in an elastic matrix and smooth muscle cells. Remodeling of the structural …

Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …

In-vivo estimation of mechanical properties of the myocardium is essential for patient-
specific diagnosis and prognosis of cardiac disease involving myocardial remodeling …

Among the three layers of the aortic wall, the media is primarily responsible for its
mechanical properties, but the adventitia prevents the aorta from overstretching and …

The ascending thoracic aortic aneurysm (ATAA) is a permanent dilatation of the vessel with
a high risk of adverse events, and shows heterogeneous properties. To investigate regional …

Computational biomechanics plays an important role in biomedical engineering: using
modeling to understand pathophysiology, treatment and device design. While experimental …