Mathematical modeling of release kinetics from supramolecular drug delivery systems
Embedding of active substances in supramolecular systems has as the main goal to ensure
the controlled release of the active ingredients. Whatever the final architecture or entrapment …
the controlled release of the active ingredients. Whatever the final architecture or entrapment …
Mathematical models as tools to predict the release kinetic of fluorescein from lyotropic colloidal liquid crystals
In this study, we investigated the release kinetic of fluorescein from colloidal liquid crystals
made from monoglyceride and different non-ionic surfactants. The crystals were …
made from monoglyceride and different non-ionic surfactants. The crystals were …
Development and characterization of orally disintegrating tablets containing a captopril-cyclodextrin complex
Captopril is the first angiotensin I-converting enzyme inhibitor widely used for the treatment
of hypertension. Based on the well-known benefits of cyclodextrin inclusion complexes, the …
of hypertension. Based on the well-known benefits of cyclodextrin inclusion complexes, the …
Formulation of chewable tablets containing carbamazepine-β-cyclodextrin inclusion complex and f-melt disintegration excipient. The mathematical modeling of the …
Due to its low solubility, carbamazepine (CBZ) exhibits slow and incomplete release in the
gastrointestinal tract and, hence, variable pharmacokinetics and pharmacodynamic effect …
gastrointestinal tract and, hence, variable pharmacokinetics and pharmacodynamic effect …
[HTML][HTML] Exploring Deep Eutectic Solvents as Pharmaceutical Excipients: Enhancing the Solubility of Ibuprofen and Mefenamic Acid
Objectives: The study explores the potential of various deep eutectic solvents (DESs) to
serve as drug delivery systems and pharmaceutical excipients. The research focuses on two …
serve as drug delivery systems and pharmaceutical excipients. The research focuses on two …
Biopharmaceutical profiling of new antitumor pyrazole derivatives
Several new pyrazole derivatives have demonstrated promising antiproliferative and
cytotoxic effects, but their poor solubility raised concerns over possible biopharmaceutical …
cytotoxic effects, but their poor solubility raised concerns over possible biopharmaceutical …
Estimation of the In Vivo Release of Amiodarone From the Pharmacokinetics of Its Active Metabolite and Correlation With Its In Vitro Release
MR Shleghm, C Mircioiu, VA Voicu, I Mircioiu… - Frontiers in …, 2021 - frontiersin.org
Due to its very low water solubility and complex pharmacokinetics, a reliable point-to-point
correlation of its in vitro release with its pharmacokinetics has not been achieved so far with …
correlation of its in vitro release with its pharmacokinetics has not been achieved so far with …
Effect of a new synergistic combination of low doses of acetylsalicylic acid, caffeine, acetaminophen, and chlorpheniramine in acute low back pain
VA Voicu, C Mircioiu, C Plesa, M Jinga… - Frontiers in …, 2019 - frontiersin.org
The present paper continues a more complex research related to the increased synergism in
terms of both anti-inflammatory and analgesic effect obtained by the addition of …
terms of both anti-inflammatory and analgesic effect obtained by the addition of …
[PDF][PDF] Characterization of nimesulide and development of immediate release tablets
This paper aims to characterize nimesulide raw materials from different manufacturers and
to develop immediate release tablets, in order to register a generic product. Also, raw …
to develop immediate release tablets, in order to register a generic product. Also, raw …
[PDF][PDF] Kinetic analysis of in vitro drug release from valproic acid and sodium valproate suppositories
A Ciurba, N Todoran, A Tăurean, P Antonoaea… - …, 2014 - farmaciajournal.com
The present study aims to develop new formulations of suppositories containing valproic
acid or sodium valproate for the pediatric use of anticonvulsant therapy. Seven formulations …
acid or sodium valproate for the pediatric use of anticonvulsant therapy. Seven formulations …