[HTML][HTML] Low dose ionizing radiation effects on the immune system

K Lumniczky, N Impens, G Armengol, S Candéias… - Environment …, 2021 - Elsevier
Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Low-dose or low-dose-rate ionizing radiation–induced bioeffects in animal models

FR Tang, WK Loke, BC Khoo - Journal of radiation research, 2017 - academic.oup.com
Animal experimental studies indicate that acute or chronic low-dose ionizing radiation
(LDIR)(≤ 100 mSv) or low-dose-rate ionizing radiation (LDRIR)(< 6 mSv/h) exposures may …

[HTML][HTML] Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic …

JS Helm, RA Rudel - Archives of toxicology, 2020 - Springer
Abstract Knowledge about established breast carcinogens can support improved and
modernized toxicological testing methods by identifying key mechanistic events. Ionizing …

[HTML][HTML] The scientific basis for the use of the linear no-threshold (LNT) model at low doses and dose rates in radiological protection

D Laurier, Y Billarand, D Klokov… - Journal of Radiological …, 2023 - iopscience.iop.org
The linear no-threshold (LNT) model was introduced into the radiological protection system
about 60 years ago, but this model and its use in radiation protection are still debated today …

[HTML][HTML] Re-evaluation of the linear no-threshold (LNT) model using new paradigms and modern molecular studies

S Tharmalingam, S Sreetharan, AL Brooks… - Chemico-Biological …, 2019 - Elsevier
The linear no-threshold (LNT) model is currently used to estimate low dose radiation (LDR)
induced health risks. This model lacks safety thresholds and postulates that health risks …

[HTML][HTML] A radiosensitivity gene signature in predicting glioma prognostic via EMT pathway

J Meng, P Li, Q Zhang, Z Yang, S Fu - Oncotarget, 2014 - ncbi.nlm.nih.gov
A 31-gene signature derived by integrating four different microarray experiments, has been
found to have a potential for predicting radiosensitivity of cancer cells, but it was seldom …

Repeated contrast-enhanced micro-CT examinations decrease animal welfare and influence tumor physiology

J Baier, A Rix, M Darguzyte, RM Girbig… - Investigative …, 2023 - journals.lww.com
Objectives Computed tomography (CT) imaging is considered relatively safe and is often
used in preclinical research to study physiological processes. However, the sum of low-dose …

Nested case-control study of occupational radiation exposure and breast and esophagus cancer risk among medical diagnostic X ray workers in Jiangsu of China

FR Wang, QQ Fang, WM Tang, XS Xu… - Asian Pacific Journal …, 2015 - koreascience.kr
Medical diagnostic X-ray workers are one occupational group that expose to the long-term
low-dose external radiation over their working lifetime, and they may under risk of different …

Low dose radiation, inflammation, cancer and chemoprevention

A Maqsudur Rashid, L Ramalingam… - … Journal of Radiation …, 2019 - Taylor & Francis
Purpose: Recently, new studies have brought to light the potential risks of low dose radiation
(LDR) in cancer. In this review, we discuss in detail the detrimental effects of LDR in some …

Individual variations in dose response for spatial memory learning among outbred wistar rats exposed from 5 to 20 cGy of 56Fe particles

AJ Wyrobek, RA Britten - Environmental and Molecular …, 2016 - Wiley Online Library
Exposures of brain tissue to ionizing radiation can lead to persistent deficits in cognitive
functions and behaviors. However, little is known about the quantitative relationships …