Oxidative stress is caused by the imbalance between the generation of free radicals/reactive
oxygen species (ROS) and the antioxidant defense systems, which can activate various …

The present study determines the potential antioxidants in Moutan Cortex (MC) and predicts
its targets of anti-oxidative activities. The quantitative analysis and the free radical …

Background Cytokines were correlated with survival and disease progression in acute
myeloid leukemia (AML). We aimed to evaluate the multivariate effect of TNF‐α rs361525 …

Ibrutinib is a tyrosine kinase inhibitor used in the treatment of a variety of lymphoid
malignancies, including chronic lymphocytic leukemia (CLL). Drugs inhibiting B-cell …

Angiogenesis process contributes to the pathogenesis of B-cell chronic lymphocytic
leukemia (B-CLL) being the levels of VEGFA and bFGF higher in patients than in healthy …

Cytokines are potent molecules produced mainly by specific activated immune cells to
control inflammatory responses besides other biologic processes. Although active …

Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related death
worldwide. Studies have shown that the tumour necrosis factor alpha (TNF‐α) plays an …

Background: several studies have been performed to investigate the association of TNF-α-
308G> ASNP and CLL susceptibility However, the results are inconsistent. This study aimed …

Background: Genetic factors like single nucleotide polymorphisms (SNPs) may play an
important role in the etiology of chronic lymphocytic leukemia (CLL). Mutations in Toll like …

One of the most common endocrine disorders in children and adolescents, Diabetes mellitus
(DM), is a chronic, polygenic and complex illness. Based on etiology, DM can be divided into …