Abstract Three component Kabachnik-Fields reaction under sonochemical conditions was
utilized for synthesizing library of electronically diverse aryl substituted α …

Edifenphos is an important organophosphate pesticide with many antifungal and anti-
insecticidal properties but it may cause potential hazards to human health. In this work, we …

BCL2, an antiapoptotic protein, is overexpressed in many cancers, making it a good cancer
treatment target. In 30 years, few BCL2 targeting agents have shown clinical significance …

A pharmacophoric motif decorated with supramolecular functionalities (TZT) was designed
for potential interaction with biological targets. Main insights of this work include the …

To improve the antiproliferative effect of ALC67 (diastereomeric mixture of ethyl 2-phenyl-3-
propioloyl-1, 3-thiazolidine-4-carboxylate), its structure was modified via (i) bioisosteric …

Diastereomeric '2RS, 4R'-2-arylthiazolidine-4-carboxylic acids (ATCAs) were synthesized
and their resolution to chiraly pure N-BOC derivatives was attempted by column …

The condensation reaction of ortho-vanillin and l-cysteine leads to formation of a racemic
mixture of (2RS, 4R)-2-(2-hydroxy-3-methoxyphenyl) thiazolidine-4-carboxylic acid and not …

The activation of caspases is central to apoptotic process in living systems. Defects in
apoptosis have been implicated with carcinogenesis. Need to develop smart agents capable …

The bisthiourea copper and cadmium adipate (BTCu/CdA), and their glycine-doped
derivatives (BTCu/CdA-Gly) have been synthesized by simple mechanochemical method …

Natural attenuation mimics nature's own cleansing mechanism and offers an effective
solution for contaminant treatment under prevalent environmental conditions without …