Abstract In 1977, Mason and Williams developed the concept of the alveolar epithelial type II
(AE2) cell as a defender of the alveolus. It is well known that AE2 cells synthesise, secrete …

▪ Abstract The lung collectins, SP-A and SP-D, are important components of the innate
immune response to microbial challenge and participate in other aspects of immune and …

To determine the role of surfactant protein-A (SP-A) in host defense, the murine SP-A locus
was targeted by homologous recombination to produce mice lacking SP-A. SP-A−/− and …

The role of surfactant-associated protein (SP) A in the mediation of pulmonary responses to
bacterial lipopolysaccharide (LPS) was assessed in vivo with SP-A gene-targeted [SP …

Research over the last decade on the surfactant proteins SP‐A and SP‐D suggests roles
beyond surfactant lipid homeostasis, involving their participation in innate immune defence …

Surfactant protein A (SP-A) is a highly ordered, oligomeric glycoprotein that is secreted into
the airspaces of the lung by the pulmonary epithelium. The in vitro activities of protein …

ABSTRACT Surfactant protein A (SP‐A) is the major protein component of pulmonary
surfactant, a material secreted by the alveolar type II cell that reduces surface tension at the …

Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

The peri-implantation period is a critical time during murine development. Although the
importance of nitric oxide has been demonstrated during gestation, its role in implantation …

Pulmonary surfactant protein D (SP-D) is a collagenous C-type lectin (collectin) that is
secreted into the alveoli and distal airways of the lung. We have studied the interactions of …