Breast cancer is the most common cancer and the deadliest among women worldwide.
Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen …

Imbalance in the tissue microenvironment is the main obstacle to drug delivery and
distribution in the human body. Before penetrating the pathological tissue microenvironment …

Simple Summary Breast and prostate cancers are serious public health issues that create
considerable burden to both people and healthcare systems worldwide. Cancer is a …

Breast cancer remains the most frequently diagnosed malignancy among women
worldwide. Although effective, numerous treatment strategies have been developed, which …

The adult human breast is comprised of an intricate network of epithelial ducts and lobules
that are embedded in connective and adipose tissue,–. Although most previous studies have …

In a substantial number of patients, ductal carcinoma in situ (DCIS) of the breast will never
progress to invasive ductal carcinoma, and these patients are often overtreated under the …

Simple Summary Cancer heterogeneity, which occurs in most cancer patients, has been
known and studied by experienced pathologists since the early 19th century. Intratumoral …

The stromal microenvironment regulates mammary gland development and tumorigenesis.
In normal mammary glands, the stromal microenvironment encompasses the ducts and …

Context Breast development is important for most trans women. An important limitation of
current breast development measurement methods is that these do not allow for 3D volume …

Intratumoral heterogeneity is caused by genomic instability and phenotypic plasticity, but
how these features co-evolve remains unclear. SOX10 is a neural crest stem cell (NCSC) …