The liver is not oblivious to the passage of time, as ageing is a major risk factor for the
development of acute and chronic liver diseases. Ageing produces alterations in all hepatic …

The biliary epithelial cells, also known as cholangiocytes, line the intra-and extrahepatic bile
ducts, forming a barrier between intra-and extra-ductal environments. Cholangiocytes are …

Hepatocellular carcinoma (HCC) represents a worryingly increasing cause of malignancy-
related mortality, while Metabolic Associated Fatty Liver Disease (MAFLD) is going to …

Introduction We aimed to highlight the effects of senotherapy on the prevention and
treatment of cancer in older individuals. The aim of senotherapy is to eliminate senescent …

Hepatocellular carcinoma (HCC) poses a significant clinical challenge, necessitating the
integration of immunotherapeutic approaches. Palbociclib, a selective CDK4/6 inhibitor, has …

Hepatocellular carcinoma (HCC) is one of the most aggressive types of liver cancer, and it is
frequently associated with upregulated c‐Myc expression. Sorafenib (Sor) is commonly used …

This comprehensive review navigates the complex relationship between cellular aging,
senescence, and cancer, unraveling the determinants of cellular fate. Beginning with an …

The high mortality rate and postoperative recurrence of hepatocellular carcinoma (HCC)
contribute to the burden on society and healthcare. The prognostic value and underlying …

Background: Gliomas and hepatocellular carcinoma (HCC) are difficult to treat with short
survival rates despite current therapies. The need for new treatments is urgent, and …

While a broad range of treatment opinions is currently available for patients with HCC,
including surgical interventions (such as liver resection or transplantation), ablation, intra …