[HTML][HTML] Gastrointestinal manifestations of systemic sclerosis

IM McFarlane, MS Bhamra, A Kreps… - Rheumatology …, 2018 - ncbi.nlm.nih.gov
Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibroproliferative
alterations of the microvasculature leading to fibrosis and loss of function of the skin and …

Gastrointestinal manifestations of systemic sclerosis

AB Shreiner, C Murray, C Denton… - Journal of scleroderma …, 2016 - journals.sagepub.com
In patients with systemic sclerosis (SSc), gastrointestinal (GI)-tract involvement is almost
universal. Any segment of the GI tract from mouth to anus can be involved, and GI symptoms …

Gastrointestinal involvement in systemic sclerosis: pathogenesis, assessment and treatment

ER Volkmann, Z McMahan - Current opinion in rheumatology, 2022 - journals.lww.com
Here, we provide important updates pertaining to the risk stratification, assessment,
diagnosis and management of SSc patients with gastrointestinal symptoms. These findings …

Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management

ZH McMahan, S Kulkarni, J Chen, JZ Chen… - Nature Reviews …, 2023 - nature.com
Nearly all patients with systemic sclerosis (SSc) are negatively affected by dysfunction in the
gastrointestinal tract, and the severity of gastrointestinal disease in SSc correlates with high …

pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis

S Kumar, J Singh, S Rattan, AJ DiMarino… - Alimentary …, 2017 - Wiley Online Library
Background Gastrointestinal tract (GIT) involvement is a common cause of debilitating
symptoms in patients with systemic sclerosis (SSc). There are no disease modifying …

[HTML][HTML] When natural antibodies become pathogenic: autoantibodies targeted against G protein-coupled receptors in the pathogenesis of systemic sclerosis

R Akbarzadeh, A Müller, JY Humrich… - Frontiers in …, 2023 - frontiersin.org
Systemic sclerosis (SSc) is a chronic, multisystem connective tissue, and autoimmune
disease with the highest case-specific mortality and complications among rheumatic …

[HTML][HTML] Gastrointestinal involvement in systemic sclerosis: an update

JB Miller, N Gandhi, J Clarke… - JCR: Journal of Clinical …, 2018 - journals.lww.com
Systemic sclerosis is an autoimmune disease characterized by vasculopathy, progressive
fibrosis of the skin, and internal organ dysfunction. Gastrointestinal (GI) disease is the most …

Systemic sclerosis: gastrointestinal disease and its management

G Gyger, M Baron - Rheumatic Disease Clinics, 2015 - rheumatic.theclinics.com
The gastrointestinal (GI) tract is the most frequently involved internal organ in systemic
sclerosis (SSc), affecting more than 90% of patients. 1 The most frequent GI involvement is …

Intestinal involvement in systemic sclerosis: a clinical review

LI Sakkas, T Simopoulou, D Daoussis… - Digestive diseases and …, 2018 - Springer
Systemic sclerosis (SSc) is a chronic systemic disease characterized by microvasculopathy,
autoantibodies, and extensive fibrosis. Intestinal involvement is frequent in SSc and …

Role of muscarinic-3 receptor antibody in systemic sclerosis: correlation with disease duration and effects of IVIG

S Kumar, J Singh, R Kedika… - American Journal …, 2016 - journals.physiology.org
Gastrointestinal dysmotility in systemic sclerosis (SSc) is associated with autoantibodies
against muscarinic-3 receptor (M3-R). We investigated the temporal course of the site of …