Pathobiology of Japanese encephalitis virus infection

KB Sharma, S Vrati, M Kalia - Molecular Aspects of Medicine, 2021 - Elsevier
Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …

[HTML][HTML] Molecular pathogenesis of Japanese encephalitis and possible therapeutic strategies

S Kumar, A Verma, P Yadav, SK Dubey, EI Azhar… - Archives of …, 2022 - Springer
Japanese encephalitis virus (JEV), a single-stranded, enveloped RNA virus, is a health
concern across Asian countries, associated with severe neurological disorders, especially in …

[HTML][HTML] Japanese encephalitis virus: an update on the potential antivirals and vaccines

KS Srivastava, V Jeswani, N Pal, B Bohra… - Vaccines, 2023 - mdpi.com
Japanese encephalitis virus (JEV) is the causal agent behind Japanese encephalitis (JE), a
potentially severe brain infection that spreads through mosquito bites. JE is predominant …

[HTML][HTML] Mechanistic insights into the Japanese encephalitis virus RNA dependent RNA polymerase protein inhibition by bioflavonoids from Azadirachta indica

VD Dwivedi, A Singh, SA El-Kafraway, TA Alandijany… - Scientific Reports, 2021 - nature.com
Japanese encephalitis (JE) virus is a flavivirus causing encephalitis causing neurological
damage. RNA-dependent-RNA-polymerase (RdRp) is responsible for genome replication …

[HTML][HTML] Implications of microorganisms in Alzheimer's disease

P Yadav, YH Lee, H Panday, S Kant, N Bajwa… - Current issues in …, 2022 - mdpi.com
Alzheimer's disease (AD) is a deadly brain degenerative disorder that leads to brain
shrinkage and dementia. AD is manifested with hyperphosphorylated tau protein levels and …

[HTML][HTML] Molecular mechanism and role of Japanese encephalitis virus infection in central nervous system-mediated diseases

P Yadav, P Chakraborty, NK Jha, S Dewanjee, AK Jha… - Viruses, 2022 - mdpi.com
The Japanese encephalitis virus (JEV) is the most common cause of neurodegenerative
disease in Southeast Asia and the Western Pacific region; approximately 1.15 billion people …

[HTML][HTML] Antiviral drug research for Japanese encephalitis: an updated review

S Joe, AAA Salam, U Neogi, PP Mudgal - Pharmacological Reports, 2022 - Springer
Japanese encephalitis (JE) caused by the Japanese encephalitis virus (JEV) is one of Asia's
most common viral encephalitis. JEV is a flavivirus, common in rural and sub-urban regions …

[HTML][HTML] Antiviral activity of ouabain against a Brazilian Zika virus strain

DCM Carvalho, PG da Silva, WM Dantas… - Scientific Reports, 2022 - nature.com
Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently,
no specific vaccines or antivirals are available to treat the ZIKV infection. Ouabain, a …

Screening of botanical drugs against Lassa virus entry

Y Liu, J Guo, J Cao, G Zhang, X Jia, P Wang… - Journal of …, 2021 - Am Soc Microbiol
Lassa virus (LASV) belongs to the Old World genus Mammarenavirus (family Arenaviridae).
At present, there are no approved drugs or vaccines specific for LASV. In this study, high …

[HTML][HTML] Screening of a small molecule compound library identifies Toosendanin as an inhibitor against bunyavirus and SARS-CoV-2

S Li, M Ye, Y Chen, Y Zhang, J Li, W Liu, H Li… - Frontiers in …, 2021 - frontiersin.org
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus
causing serious infectious disease with a high case-fatality of up to 50% in severe cases …