Bone is a richly vascularized connective tissue. As the main source of oxygen, nutrients,
hormones, neurotransmitters and growth factors delivered to the bone cells, vasculature is …

Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Three-dimensional (3D) bioprinting is a promising technology for manufacturing cell-laden
tissue-engineered constructs. Larger tissue substitutes, however, require a vascularized …

Angiogenesis, the formation of new capillaries from existing ones, is a fundamental process
in regenerative medicine and tissue engineering. While it is known to be affected by …

Despite the recent advances in the development of bone graft substitutes, treatment of
critical size bone defects continues to be a significant challenge, especially in the elderly …

The recent development of tissue engineering provides exciting new perspectives for the
replacement of failing organs and the repair of damaged tissues. Perivascular cells …

The ideal tissue engineering (TE) strategy for ligament regeneration should recapitulate the
bone–calcified cartilage–fibrocartilage–soft tissue interface. Aligned electrospun-fibers have …

Millions of people worldwide suffer from trauma-or age-related orthopedic diseases such as
osteoarthritis, osteoporosis, or cancer. Tissue Engineering (TE) and Regenerative Medicine …

Large bone defect treatment represents a great challenge due to the difficulty of functional
and esthetic reconstruction. Tissue-engineered bone grafts created by in vitro manipulation …

Purpose: The aims of the study were (1) to evaluate the fitting of three different aligners
(Invisalign [Align Technology, Santa Clara, CA, USA], CA Clear Aligner [Scheu-Dental …