Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye
A Monavarfeshani, W Yan, C Pappas… - Proceedings of the …, 2023 - National Acad Sciences
Although the visual system extends through the brain, most vision loss originates from
defects in the eye. Its central element is the neural retina, which senses light, processes …
defects in the eye. Its central element is the neural retina, which senses light, processes …
Tissue Engineering of Outer Blood Retina Barrier for Therapeutic Development
Age related macular degeneration and other retinal degenerative disorders are
characterized by disruption of the outer blood retinal barrier (oBRB) with subsequent …
characterized by disruption of the outer blood retinal barrier (oBRB) with subsequent …
VDAC in Retinal Health and Disease
Y Xu, SR Tummala, X Chen, N Vardi - Biomolecules, 2024 - mdpi.com
The retina, a tissue of the central nervous system, is vital for vision as its photoreceptors
capture light and transform it into electrical signals, which are further processed before they …
capture light and transform it into electrical signals, which are further processed before they …
[HTML][HTML] Age-and sex-divergent translatomic responses of the mouse retinal pigmented epithelium
Aging is the main risk factor for age-related macular degeneration (AMD), a retinal
neurodegenerative disease that leads to irreversible blindness, particularly in people over …
neurodegenerative disease that leads to irreversible blindness, particularly in people over …
Imaging macular carotenoids and their related proteins in the human retina with confocal resonance Raman and fluorescence microscopy
Lutein and zeaxanthin are highly concentrated at the central region of the human retina,
forming a distinct yellow spot known as the macula lutea. The delivery and retention of the …
forming a distinct yellow spot known as the macula lutea. The delivery and retention of the …
Differential gene expression between central and peripheral retinal regions in dogs and comparison with humans
MM Salzman, T Takimoto, ML Foster… - Experimental Eye …, 2024 - Elsevier
The dog retina contains a central macula-like region, and there are reports of central retinal
disorders in dogs with shared genetic etiologies with humans. Defining central/peripheral …
disorders in dogs with shared genetic etiologies with humans. Defining central/peripheral …
[HTML][HTML] Aging retinal pigmented epithelium: omics-based insights into vision decline
Senescent RPE was linked to the onset of AMD, with senolytic agents assessed as potential
treatments for AMD [7]. A fact that has been seldom considered among the plethora of …
treatments for AMD [7]. A fact that has been seldom considered among the plethora of …
Location of Retinal Pigment Epithelial Cells in the Eye Is Critical to Their Function
G Malek - The American Journal of Pathology, 2023 - ASIP
The eye is an extension of the brain and a highly sophisticated sensory organ. The intricacy
of the eye is well appreciated on examination of the exquisite posterior pole, composed of …
of the eye is well appreciated on examination of the exquisite posterior pole, composed of …
Age-and Sex-Divergent Translatomic Responses of the Retinal Pigmented Epithelium
Aging is the main risk factor for age-related macular degeneration (AMD), a retinal
neurodegenerative syndrome that leads to irreversible blindness, particularly in people over …
neurodegenerative syndrome that leads to irreversible blindness, particularly in people over …