[HTML][HTML] Anthelmintic resistance in equine nematodes: Current status and emerging trends

MK Nielsen - International Journal for Parasitology: Drugs and Drug …, 2022 - Elsevier
Anthelmintic resistance is reported in equine nematodes with increasing frequency in recent
years, and no new anthelmintic classes have been introduced during the past 40 years. This …

[HTML][HTML] Perspectives on the utility of moxidectin for the control of parasitic nematodes in the face of developing anthelmintic resistance

RK Prichard, TG Geary - International Journal for Parasitology: Drugs and …, 2019 - Elsevier
Macrocyclic lactone (ML) anthelmintics are the most important class of anthelmintics
because of our high dependence on them for the control of nematode parasites and some …

[HTML][HTML] Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised …

NO Opoku, DK Bakajika, EM Kanza, H Howard… - The Lancet, 2018 - thelancet.com
Background The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease
that is primarily endemic in sub-Saharan Africa, have motivated large morbidity and …

Moxidectin: an oral treatment for human onchocerciasis

P Milton, JID Hamley, M Walker… - Expert Review of Anti …, 2020 - Taylor & Francis
Introduction Moxidectin is a milbemycin endectocide recently approved for the treatment of
human onchocerciasis. Onchocerciasis, earmarked for elimination of transmission, is a …

Ivermectin: From theory to clinical application

DS Ashour - International journal of antimicrobial agents, 2019 - Elsevier
Approximately 250 million people have been using ivermectin (IVM) annually to combat
many parasitic diseases including filariasis, onchocerciasis, strongyloidiasis, scabies and …

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity

SR Doyle, C Bourguinat… - PLoS neglected …, 2017 - journals.plos.org
Background Treatment of onchocerciasis using mass ivermectin administration has reduced
morbidity and transmission throughout Africa and Central/South America. Mass drug …

Attitudes of potential recipients toward emerging visual prosthesis technologies

V Karadima, EA Pezaris, JS Pezaris - Scientific Reports, 2023 - nature.com
With the advent of multiple visual prosthesis devices to treat blindness, the question of how
potential patients view such interventions becomes important in order to understand the …

A Randomized, Single-Ascending-Dose, Ivermectin-Controlled, Double-Blind Study of Moxidectin in Onchocerca volvulus Infection

K Awadzi, NO Opoku, SK Attah… - PLoS neglected …, 2014 - journals.plos.org
Background Control of onchocerciasis as a public health problem in Africa relies on annual
mass ivermectin distribution. New tools are needed to achieve elimination of infection. This …

Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa

G Gebrezgabiher, Z Mekonnen… - Infectious diseases of …, 2019 - mednexus.org
Background: Onchocerciasis (river blindness), caused by the filarial worm species
Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public …

[HTML][HTML] Research for new drugs for elimination of onchocerciasis in Africa

AC Kuesel - International Journal for Parasitology: Drugs and Drug …, 2016 - Elsevier
Onchocerciasis is a parasitic, vector borne disease caused by the filarial nematode
Onchocerca volvulus. More than 99% of the population at risk of infection live in Africa …