Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells
representing the interface between blood cells on the one side and hepatocytes and hepatic …

Glomerular endothelial cell (GEnC) fenestrations are analogous to podocyte filtration slits,
but their important contribution to the glomerular filtration barrier has not received …

This update focuses on two main topics. First, recent developments in our understanding of
liver sinusoidal endothelial cell (LSEC) function will be reviewed, specifically elimination of …

The accumulation of LDL-derived cholesterol in the artery wall is the initiating event that
causes atherosclerosis. However, the mechanisms that lead to the initiation of …

Various factors, including viral and bacterial infections, autoimmune responses, diabetes,
drugs, alcohol abuse, and fat deposition, can damage liver tissue and impair its function …

Sphingosine kinase 1 (SphK1)/Sphingosine-1-phosphate (S1P)/S1PRs signaling pathway is
known to involve the advancement of liver fibrosis. Exosomal SphK1 promotes hepatic …

The role of podocytes in the development and progression of glomerular disease has been
extensively investigated in the past decade. However, the importance of glomerular …

Fenestrations are pores within liver sinusoidal endothelial cells (LSECs) that enable the
transfer of substrates (particularly insulin and lipoproteins) between blood and hepatocytes …

Fenestrations are pores in liver sinusoidal endothelial cells that filter substrates and debris
between the blood and hepatocytes. Fenestrations have significant roles in aging and the …

Since the first descriptions of hepatocyte-released exosome-like vesicles in 2008, the
number of publications describing Extracellular Vesicles (EVs) released by liver cells in the …