Cardiovascular disease risk factor control as primary prevention in patients with type 2
diabetes mellitus has changed substantially in the past few years. The purpose of this …

Executive summary Despite the improvements in outcomes for cardiovascular disease
(CVD) over the last 20 years, it remains the major cause of morbidity and mortality in the …

Importance Low-dose aspirin is used for primary cardiovascular disease prevention and
may have benefits for colorectal cancer prevention. Objective To review the benefits and …

Increasing evidence indicates that reactive oxygen species (ROS), consisting of superoxide,
hydrogen peroxide, and multiple others, do not only cause oxidative stress, but rather may …

Platelets are small anucleate cell fragments that circulate in blood playing crucial role in
managing vascular integrity and regulating hemostasis. Platelets are also involved in the …

Various nutritional, behavioral, and pharmacological interventions have been previously
shown to extend life span in diverse model organisms, including Saccharomyces cerevisiae …

Background: Cardiovascular disease (CVD) is the leading cause of death in the United
States. Purpose: To update a systematic review about the benefits of aspirin for the primary …

Diabetic nephropathy is the leading cause of kidney disease in patients starting renal
replacement therapy and affects∼ 40% of type 1 and type 2 diabetic patients. It increases …

Diabetes is a chronic illness that re-quires continuing medical care and patient self-
management education to prevent acute complications and to reduce the risk of long-term …

Recent evidence suggests that calorie restriction and specifically reduced glucose
metabolism induces mitochondrial metabolism to extend life span in various model …