[HTML][HTML] Targeting AMPK with Irisin: Implications for metabolic disorders, cardiovascular health, and inflammatory conditions—A systematic review

LF Laurindo, VD Rodrigues, LF Laurindo, LMA Cherain… - Life Sciences, 2024 - Elsevier
Irisin-based interventions have gained attention for their potential to modulate the adenosine
monophosphate (AMP)-activated protein kinase (AMPK) pathway in various diseases …

Structured presurgery prehabilitation for aged patients undergoing elective surgery significantly improves surgical outcomes and reduces cost: a nonrandomized …

FH Koh, CH Loh, WJ Tan, LML Ho… - Nutrition in clinical …, 2022 - Wiley Online Library
Background With increasing global life expectancy, the number of major surgeries
performed on aged adults invariably increases. This study aimed to examine the …

In people with type 2 diabetes, sarcopenia is associated with the incidence of cardiovascular disease: A prospective cohort study from the UK Biobank

J Boonpor, JP Pell, FK Ho… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim To investigate the association of sarcopenia with cardiovascular disease (CVD)
incidence in people with type 2 diabetes. Materials and Methods A prospective cohort study …

Association between serum FGF21 level and sarcopenia in older adults

HW Jung, JH Park, DA Kim, IY Jang, SJ Park, JY Lee… - Bone, 2021 - Elsevier
Background With emerging basic research evidence suggesting that fibroblast growth factor
(FGF) 21 is a catabolic molecule on muscle metabolism, we aimed to analyze the serum …

Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats

NR Kerr, CW Mossman, CH Chou… - Journal of Applied …, 2024 - journals.physiology.org
Alzheimer's disease (AD) is the fifth leading cause of death in older adults, and treatment
options are severely lacking. Recent findings demonstrate a strong relationship between …

Association of FGF‐19 and FGF‐21 levels with primary sarcopenia

R Bag Soytas, V Suzan, P Arman… - Geriatrics & …, 2021 - Wiley Online Library
Aim Serum fibroblast growth factor (FGF)‐19 and FGF‐21 levels have been reported to be
associated with muscle hemostasis. This study aims to explore the relationship between the …

Exploring the correlation between serum fibroblast growth factor-21 levels and Sarcopenia: a systematic review and meta-analysis

H Liu, X He, XY Deng, JL Yan - BMC Musculoskeletal Disorders, 2023 - Springer
Background Fibroblast growth factor 21 (FGF-21) plays an important role in the growth and
metabolism of skeletal muscle cells. This study aims to systemically review the evidence …

Prediction of the Risk of Bone Mineral Density Decrease in Type 2 Diabetes Mellitus Patients Based on Traditional Multivariate Logistic Regression and Machine …

J Zhang, Z Xu, Y Fu, L Chen - Diabetes, Metabolic Syndrome and …, 2023 - Taylor & Francis
Purpose There remains a lack of a machine learning (ML) model incorporating body
composition to assess the risk of bone mineral density (BMD) decreases in type 2 diabetes …

[HTML][HTML] Association between type 2 diabetes and chronic low back pain in general practices in Germany

L Jacob, W Rathmann, A Koyanagi, JM Haro… - BMJ Open Diabetes …, 2021 - drc.bmj.com
Introduction There are conflicting results on the association between type 2 diabetes and
chronic low back pain (CLBP). Therefore, the goal was to investigate the relationship …

Apocynin attenuates diabetes-induced skeletal muscle dysfunction by mitigating ROS generation and boosting antioxidant defenses in fast-twitch and slow-twitch …

S Sánchez-Duarte, R Montoya-Pérez… - Life, 2022 - mdpi.com
In response to diabetes mellitus, skeletal muscle is negatively affected, as is evident by
reduced contractile force production, increased muscle fatigability, and increased levels of …