The prefrontal cortex, pathological anxiety, and anxiety disorders

MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

Space, time, and fear: survival computations along defensive circuits

D Mobbs, DB Headley, W Ding, P Dayan - Trends in cognitive sciences, 2020 - cell.com
Naturalistic observations show that decisions to avoid or escape predators occur at different
spatiotemporal scales and that they are supported by different computations and neural …

Resource-rational analysis: Understanding human cognition as the optimal use of limited computational resources

F Lieder, TL Griffiths - Behavioral and brain sciences, 2020 - cambridge.org
Modeling human cognition is challenging because there are infinitely many mechanisms
that can generate any given observation. Some researchers address this by constraining the …

Resilience after trauma: The role of memory suppression

A Mary, J Dayan, G Leone, C Postel, F Fraisse, C Malle… - Science, 2020 - science.org
INTRODUCTION One of the fundamental questions in clinical neuroscience is why some
individuals can cope with traumatic events, while others remain traumatized by a haunting …

A model for learning based on the joint estimation of stochasticity and volatility

P Piray, ND Daw - Nature communications, 2021 - nature.com
Previous research has stressed the importance of uncertainty for controlling the speed of
learning, and how such control depends on the learner inferring the noise properties of the …

Naturalistic reinforcement learning

T Wise, K Emery, A Radulescu - Trends in Cognitive Sciences, 2023 - cell.com
Humans possess a remarkable ability to make decisions within real-world environments that
are expansive, complex, and multidimensional. Human cognitive computational …

Altered learning under uncertainty in unmedicated mood and anxiety disorders

J Aylward, V Valton, WY Ahn, RL Bond… - Nature human …, 2019 - nature.com
Anxiety is characterized by altered responses under uncertain conditions, but the precise
mechanism by which uncertainty changes the behaviour of anxious individuals is unclear …

The temporal dynamics of opportunity costs: A normative account of cognitive fatigue and boredom.

M Agrawal, MG Mattar, JD Cohen, ND Daw - Psychological review, 2022 - psycnet.apa.org
Cognitive fatigue and boredom are two phenomenological states that reflect overt task
disengagement. In this article, we present a rational analysis of the temporal structure of …

Individual differences in naturalistic learning link negative emotionality to the development of anxiety

WJ Villano, NI Kraus, TR Reneau, BA Jaso, AR Otto… - Science …, 2023 - science.org
Organisms learn from prediction errors (PEs) to predict the future. Laboratory studies using
small financial outcomes find that humans use PEs to update expectations and link …

Increased and biased deliberation in social anxiety

LE Hunter, EA Meer, CM Gillan, M Hsu… - Nature Human …, 2022 - nature.com
A goal of computational psychiatry is to ground symptoms in basic mechanisms. Theory
suggests that avoidance in anxiety disorders may reflect dysregulated mental simulation, a …