Merging the versatile functionalities of boronic acid with peptides

Y Tan, J Wu, L Song, M Zhang, CJ Hipolito… - International journal of …, 2021 - mdpi.com
Peptides inherently feature the favorable properties of being easily synthesized, water-
soluble, biocompatible, and typically non-toxic. Thus, boronic acid has been widely …

A boron delivery antibody (BDA) with boronated specific residues: new perspectives in boron neutron capture therapy from an in silico investigation

A Rondina, P Fossa, A Orro, L Milanesi, A De Palma… - Cells, 2021 - mdpi.com
Boron Neutron Capture Therapy (BNCT) is a tumor cell-selective radiotherapy based on a
nuclear reaction that occurs when the isotope boron-10 (10B) is radiated by low-energy …

Peptide Boronic Acids by Late‐Stage Hydroboration on the Solid Phase

M Werner, J Brinkhofer, L Hammermüller… - Advanced …, 2024 - Wiley Online Library
Organoboron compounds have a wide range of applications in numerous research fields,
and metmhods to incorporate them in biomolecules are much sought after. Here, on‐resin …

Synthesis and Application of Constrained Amidoboronic Acids Using Amphoteric Boron-Containing Building Blocks

HS Soor, DB Diaz, KY Tsui, K Calvopina… - The Journal of …, 2021 - ACS Publications
Amidoboronic acid-containing peptidomimetics are an important class of scaffolds in
chemistry and drug discovery. Despite increasing interest in boron-based enzyme inhibitors …

A tandem process for the synthesis of β-aminoboronic acids from aziridines with haloamine intermediates

S Park, J Koo, W Kim, HG Lee - Chemical Communications, 2022 - pubs.rsc.org
An unprecedented synthetic strategy is devised to generate β-aminoboronic acids from
aziridines via a sequential process involving 1, 2-iodoamine formation and radical borylation …

Synthesis of Fluorinated Aminoalkylboronic Acids from Amphoteric α‐Boryl Aldehydes

HS Soor, DB Diaz, KI Burton, AK Yudin - Angewandte Chemie, 2021 - Wiley Online Library
Our ongoing search for underdeveloped functional group combinations has brought to light
α‐fluorinated aminoalkylboronic acids, a new class of molecules featuring the B‐CF linkage …

Synthesis and applications of aminoboronic acids

V Trudel - 2024 - search.proquest.com
Boronic acids are a class of compounds with a wide range of applications enabled by the
coordinative ability of the boron atom. The development of new synthetic methods to access …