DNA vaccines: technology and application as anti-parasite and anti-microbial agents
JB Alarcon, GW Waine, DP McManus - Advances in parasitology, 1999 - Elsevier
DNA vaccines have been termed The Third Generation of Vaccines. The recent successful
immunization of experimental animals against a range of infectious agents and several …
immunization of experimental animals against a range of infectious agents and several …
Pharmaceutical perspectives of nonviral gene therapy
RI Mahato, LC Smith, A Rolland - Advances in genetics, 1999 - Elsevier
The use of nonviral plasmid-based gene medicines represents an attractive in vivo gene
transfer strategy that is simple and lacks many risks that are inherent to viral systems …
transfer strategy that is simple and lacks many risks that are inherent to viral systems …
Engineered nucleic acids encoding a modified erythropoietin and their expression
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Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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Engineered nucleic acids and methods of use thereof
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
Modified polynucleotides for the production of biologics and proteins associated with human disease
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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Modified polynucleotides for the production of secreted proteins
T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
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Engineered nucleic acids and methods of use thereof
S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
In vivo production of proteins
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
T Chakraborty, A De Fougerolles - US Patent 9,303,079, 2016 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …