Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

Abstract Serotonin (5-hydroxytryptamine or 5-HT) is a multifunctional bioamine with
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …

Dietary, microbial, and inflammatory factors modulate the gut-brain axis and influence
physiological processes ranging from metabolism to cognition. The gut epithelium is a …

Serotonin is an important gastrointestinal signaling molecule. It is a paracrine messenger
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …

Background & Aims The human gut microbiota can regulate production of serotonin (5-
hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms …

Serotonin (5-hydroxytryptamine; 5-HT) is abundantly present throughout the gastrointestinal
tract and stored mostly in enterochromaffin (EC) cells, which are located on the mucosal …

Celiac disease, and, more generally, gluten intolerance, is a growing problem worldwide,
but especially in North America and Europe, where an estimated 5% of the population now …

Serotonin (5-HT) is an important signaling molecule in the gut targeting enterocytes, smooth
muscles and enteric neurons. Most of the body serotonin is present in enterochromaffin …

Chemosensing in the gastrointestinal tract is less well understood than many aspects of gut
mechanosensitivity; however, it is important in the overall function of the GI tract and indeed …

The afferent innervation of the gastrointestinal (GI) tract consists of intrinsic and extrinsic
sensory neurons that respond to nutrients, chemicals or mechanical stimuli within the gut …