The mechanism of secretion and metabolism of gut-derived 5-hydroxytryptamine
N Liu, S Sun, P Wang, Y Sun, Q Hu… - International journal of …, 2021 - mdpi.com
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
The diverse metabolic roles of peripheral serotonin
Abstract Serotonin (5-hydroxytryptamine or 5-HT) is a multifunctional bioamine with
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …
[HTML][HTML] Enterochromaffin cells are gut chemosensors that couple to sensory neural pathways
Dietary, microbial, and inflammatory factors modulate the gut-brain axis and influence
physiological processes ranging from metabolism to cognition. The gut epithelium is a …
physiological processes ranging from metabolism to cognition. The gut epithelium is a …
The serotonin signaling system: from basic understanding to drug development for functional GI disorders
MD Gershon, J Tack - Gastroenterology, 2007 - Elsevier
Serotonin is an important gastrointestinal signaling molecule. It is a paracrine messenger
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …
[HTML][HTML] Human-derived Bifidobacterium dentium modulates the mammalian serotonergic system and gut–brain axis
MA Engevik, B Luck, C Visuthranukul… - Cellular and molecular …, 2021 - Elsevier
Background & Aims The human gut microbiota can regulate production of serotonin (5-
hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms …
hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms …
TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells
K Nozawa, E Kawabata-Shoda… - Proceedings of the …, 2009 - National Acad Sciences
Serotonin (5-hydroxytryptamine; 5-HT) is abundantly present throughout the gastrointestinal
tract and stored mostly in enterochromaffin (EC) cells, which are located on the mucosal …
tract and stored mostly in enterochromaffin (EC) cells, which are located on the mucosal …
Glyphosate, pathways to modern diseases II: Celiac sprue and gluten intolerance
A Samsel, S Seneff - Interdisciplinary toxicology, 2013 - sciendo.com
Celiac disease, and, more generally, gluten intolerance, is a growing problem worldwide,
but especially in North America and Europe, where an estimated 5% of the population now …
but especially in North America and Europe, where an estimated 5% of the population now …
Role of serotonin in gastrointestinal motility and irritable bowel syndrome
A Sikander, SV Rana, KK Prasad - Clinica chimica acta, 2009 - Elsevier
Serotonin (5-HT) is an important signaling molecule in the gut targeting enterocytes, smooth
muscles and enteric neurons. Most of the body serotonin is present in enterochromaffin …
muscles and enteric neurons. Most of the body serotonin is present in enterochromaffin …
Gut chemosensing: interactions between gut endocrine cells and visceral afferents
HE Raybould - Autonomic Neuroscience, 2010 - Elsevier
Chemosensing in the gastrointestinal tract is less well understood than many aspects of gut
mechanosensitivity; however, it is important in the overall function of the GI tract and indeed …
mechanosensitivity; however, it is important in the overall function of the GI tract and indeed …
Serotonin release and uptake in the gastrointestinal tract
PP Bertrand, RL Bertrand - Autonomic neuroscience, 2010 - Elsevier
The afferent innervation of the gastrointestinal (GI) tract consists of intrinsic and extrinsic
sensory neurons that respond to nutrients, chemicals or mechanical stimuli within the gut …
sensory neurons that respond to nutrients, chemicals or mechanical stimuli within the gut …