Multi-target-directed cinnamic acid hybrids targeting Alzheimer's disease

A Drakontaeidi, E Pontiki - International journal of molecular sciences, 2024 - mdpi.com
Progressive cognitive decline in Alzheimer's disease (AD) is a growing challenge. Present
therapies are based on acetylcholinesterase inhibition providing only temporary relief …

Polyphenols: Immunonutrients tipping the balance of immunometabolism in chronic diseases

C Ferreira, P Vieira, H Sá, J Malva… - Frontiers in …, 2024 - frontiersin.org
Mounting evidence progressively appreciates the vital interplay between immunity and
metabolism in a wide array of immunometabolic chronic disorders, both autoimmune and …

Molecular Aspects of Inflammation and Lipid Metabolism in Health and Disease: The Role of the Mitochondria

VN Sukhorukov, AN Orekhov - International Journal of Molecular …, 2024 - mdpi.com
Inflammation and lipid metabolism are two deeply interconnected and reciprocally regulated
major physiological processes [1, 2]. As such, both of these processes are fundamental for …